Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
|---|---|---|---|---|---|---|---|
| 1001 | ACSSSPSKHCG | TD1 | TD1 enhances the transdermal delivery of macromolecules | Franz diffusion cells | Significant increase in permeability of the peptide can be seen by the addition of ATP.The amount of protein that permeated the skin was determined with ELISA | Male SD rats skin cells | 25269793 |
| 1020 | ACSSSPSKHCG | TDN | TD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | Confocal Laser Scanning Microscopy | Significant permeability of the peptide can be seen in confocal images | Male SD rats skin cells | 23391375 |
| 1021 | ACSSKKSKHCG | TD-34 | TD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | Confocal Laser Scanning Microscopy | Significant permeability of the peptide can be seen in confocal images | Male SD rats skin cells | 23391375 |
| 1022 | ACSSSPSKHCG | TD1 | TD1 enhances the transdermal delivery of macromolecules | Franz diffusion cells, immunity fluorescence techniques | Significant permeability of the peptide can be seen. The amount of protein that permeated the skin was determined with immunity fluorescence techniques | Male SD rats skin cells | 23385091 |
| 1096 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | Fluorescence microscopy, Transmission electron microscopy | Penetrates to the stratum corneum of rat footpad 15 min after topical application. | Footpad skin of rats | 22009459 |
| 1097 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | Fluorescence microscopy, Transmission electron microscopy | Co-administered FAM-labeled siRNA gathered in the hair follicle 30 min after application | Back skin of rats | 22009459 |
| 1098 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | Fluorescence microscopy, Transmission electron microscopy | FAM-labeled siRNA and TD-1 topically co-administered penetrated from the stratum corneum to subcutaneous tissue 15 min after application | Footpad skin of rats | 22009459 |
| 1099 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | Fluorescence microscopy, Transmission electron microscopy | TD1 detected strongly from epithelial tissue to subcutaneous tissue 60 min after application | Footpad skin of rats | 22009459 |
| 1100 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | Fluorescence microscopy, Transmission electron microscopy | Both FITC-labeled TD-1 and co-administered FAM-labeled siRNA were detected strongly from epithelial tissue to subcutaneous tissue 60 min after application | Footpad skin of rats | 22009459 |
| 1101 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | RT-PCR | The level of GADPH decreased 37 % | Rat footpad skin | 22009459 |
| 1102 | ACSSSPSKHCG | TD-1 | Transdermal Delivery enhancer | RT-PCR | The level of GADPH decreased 49 % | Rat footpad skin | 22009459 |
| 1107 | ACSSSPSKHCG | TD-1 | TD1 enhances the transdermal delivery of macromolecules | Electrical stimulation of the saphenous nerve at 4 Hz for 1 min in skin pretreated with vehicle | The maximum amount of PE (Plasma Extravasation) in the control side was 68 ± 3 PIUs compared to 46 ± 2 PIUs in BoNT-A + TD-1 pretreated skin | Dorsal surface of the rat hindpaw skin | 20223589 |
| 1111 | GRKKRRQRRRPPQ | Tat | Cell penetrating peptide | Franz cell system | Kp (permeability coefficients) 6.30 in the cubic system | Porcine skin | 19733297 |
| 1112 | GRKKRRQRRRPPQ | Tat | Cell penetrating peptide | Franz cell system | Kp (permeability coefficients) 1.70 in the cubic system | Porcine skin | 19733297 |
| 1141 | ACSSSPSKHCG | TD-1 | TD1 enhances the transdermal delivery of macromolecules | Confocal Laser Scanning Microscopy, Blood glucose measurement | Significant permeability of insulin could be seen in the confocal images, TD-1 without insulin had no effect on either blood glucose or serum insulin level, indicating that the glucose-lowering effect observed with TD 1 and insulin coadministration was due to the delivered exogenous insulin and not a physiological response elicited by TD-1 | Abdominal skin of rat | 16565728 |
| 1142 | LNQEQVSPRKKC | Peptide | Peptide containing α 2-plasmin inhibitor fibrin-binding site to the free amines on the surface of the KGF molecule | Inverted fluorescence microscopy | The gradual healing of wound coould be easily visualised in th fluoresence microscopy images. Overlaid fluorescent and bright-field images of the wound show migrating cells as they degrade the fibrin matrix | Human skin equivalents were grafted to athymic mice | 16314471 |
| 1144 | TSLDASIIWAMMQN | P144 | Interferes with TGF-β1 binding to its cellular receptors on Mv1Lu cells. Potent in vivo anti-fibrotic activity in the liver of rats receiving CCl4 | Sircol Collagen Assay kit, histological and immunohistochemical studies | Dermal thickness: Bleomycin treated-180%, Bleomycin plus P144 lipogel emulsion-120%, Bleomycin plus vehicle-200%. Soluble collagen: Bleomycin treated-215%, Bleomycin plus P144 lipogel emulsion-150%, Bleomycin plus vehicle-220%. Data represent mean±SD of 10 mice per group, and the values of PBS-treated mice are set to 100%. | Shaved skin area of female C3H mice | 16117784 |
| 1152 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.12 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1153 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.054 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1154 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.02 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1155 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.06 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1156 | YKALRISRKLAK | YKAc | It is a nontransducing peptide | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1157 | WLRRASAPLPGLK | P20 | Phosphopeptide analogue of the heat shock protein (HSP) 20 | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.1 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1158 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.04 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1159 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.05 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1160 | YKALRISRKLAK | YKAc | It is a nontransducing peptide | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1161 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.046 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1162 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.055 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1163 | YKALRISRKLAK | YKAc | It is a nontransducing peptide | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1164 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.048 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1165 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0.056 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1166 | YKALRISRKLAK | YKAc | It is a nontransducing peptide | Fluorimetry analysis using Gemini SpectraMax plate reader | Transdermal delivery(nmol)- -̴0 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1167 | WLRRASAPLPGLK | P20 | Phosphopeptide analogue of the heat shock protein (HSP) 20 | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.15 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1168 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.6 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1169 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.7 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1170 | WLRRASAPLPGLK | P20 | Phosphopeptide analogue of the heat shock protein (HSP) 20 | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.05 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1171 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.9 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1172 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.98 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1173 | WLRRASAPLPGLK | P20 | Phosphopeptide analogue of the heat shock protein (HSP) 20 | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.13 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1174 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.39 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1175 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.47 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1176 | WLRRASAPLPGLK | P20 | Phosphopeptide analogue of the heat shock protein (HSP) 20 | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.01 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1177 | YARAAARQARA | YARA | Molecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.03 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1178 | YGRKKRRQRRR | TAT | HIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | Fluorimetry analysis using Gemini SpectraMax plate reader | Rate of skin penetration(nmol/cm2/h)- -̴0.1 | Freshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | 15906170 |
| 1179 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Depth of wound crater(mm)=1.35/2.0(control), Wound necrosis area(mm2)=16/27(control), Wound area(mm2)=87.5/100(control), Oedema (µm)=975/1175(control), No. of blood vessels=3/2(control), Diameter of blood vessels (µm)=900/1000(control), No. of inflammatory cells=73.5/116(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |
| 1180 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Depth of wound crater(mm)=1.85/2.0(control), Wound necrosis area(mm2)=20/27(control), Wound area(mm2)=97.5/100(control), Oedema (µm)=1100/1175(control), No. of blood vessels=2/2(control), Diameter of blood vessels (µm)=875/1000(control), No. of inflammatory cells=103.5/116(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |
| 1181 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Depth of wound crater(mm)=2.05/2.0(control), Wound necrosis area(mm2)=24.5/27(control), Wound area(mm2)=100/100(control), Oedema (µm)=1150/1175(control), No. of blood vessels=2/2(control), Diameter of blood vessels (µm)=875/1000(control), No. of inflammatory cells=123/116(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |
| 1182 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Wound area(mm2)=80/100(control), No. of blood vessels=2/0(control), Diameter of blood vessels (µm)=105/110(control), Reticulin (%)=51/21.5(control), Collagen (%)=70.5/39.5(control), Necrosis (score 0–4)=2/3(control), No. of vital follicles=58.5/20(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |
| 1183 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Wound area(mm2)=97.5/100(control), No. of blood vessels=1/0(control), Diameter of blood vessels (µm)=55/110(control), Reticulin (%)=31/21.5(control), Collagen (%)=43.5/39.5(control), Necrosis (score 0–4)=3/3(control), No. of vital follicles=34/20(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |
| 1184 | GEPPPGKPADDAGLV | Pentadecapeptide BPC157 | It consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | Macroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Parameters studied: Wound area(mm2)=97.5/100(control), No. of blood vessels=0.5/0(control), Diameter of blood vessels (µm)=40/110(control), Reticulin (%)=26/21.5(control), Collagen (%)=31.5/39.5(control), Necrosis (score 0–4)=3/3(control), No. of vital follicles=26/20(control) | Randomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | 15774286 |