Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
|---|---|---|---|---|---|---|---|
| 1002 | AAPV | AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=0.46 μg/cm2/h, Permeability coefficient=1.50×10−4Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1003 | AAPV | C6(D)-Laa-AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=2.29 μg/cm2/h, Permeability coefficient=7.6×10−4 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1004 | AAPV | C6(L)-Laa- AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=0.50 μg/cm2/h, Permeability coefficient=1.6×10−4 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1005 | AAPV | C8(D,L)-Laa-AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=10.08 μg/cm2/h, Permeability coefficient= 3.3×10−3 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1006 | AAPV | C8(D)-Laa-AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=7.42 μg/cm2/h, Permeability coefficient=1.90×10−2 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1007 | AAPV | C8(L)-Laa-AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=1.37 μg/cm2/h, Permeability coefficient=4.50×10−4 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1008 | AAPV | C10(D,L)-Laa-AAPV | It fits the P-P1 subsites of elastase and inhibits HNE competitively | Franz diffusion cell, HPLC | Epidermal flux=8.92 μg/cm2/h, Permeability coefficient=2.9×10−3 Kp(cm/h) | Human epidermal membranes were obtained by heat separation of whole skin | 24842663 |
| 1010 | GKRR | R4 (arginine-terminated peptide dendrimers) | Peptide dendrimers are wedge-like molecules comprising an amino acid branching core that is most typically decorated with various basic amino acids (e.g. Lys, His, Arg) on their head groups | Franz diffusion cell | Flux (mg/cm2/h) 25.16 ± 2.31 , Q48 (mg) 1167.05 ± 50.10 Drug content in skin (mg/cm2) 146 ± 6.44 | Human epidermal skin | 24134794 |
| 1011 | GKRR | R4 (arginine-terminated peptide dendrimers) | Peptide dendrimers are wedge-like molecules comprising an amino acid branching core that is most typically decorated with various basic amino acids (e.g. Lys, His, Arg) on their head groups | Franz diffusion cell | Flux (mg/cm2/h) 43.74 ± 4.15 , Q48(mg) 2064.72 ± 100.05 Drug content in skin (mg/cm2) 180 ± 8.23 | Human epidermal skin | 24134794 |
| 1012 | GKRR | R4 (arginine-terminated peptide dendrimers) | Peptide dendrimers are wedge-like molecules comprising an amino acid branching core that is most typically decorated with various basic amino acids (e.g. Lys, His, Arg) on their head groups | Franz diffusion cell | Flux (mg/cm2/h) 57.66 ± 4.83 , Q48(mg) 2706.53 ± 123.60, Drug content in skin (mg/cm2) 204 ± 8.41 | Human epidermal skin | 24134794 |
| 1028 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~0.5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1029 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >0.5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1030 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >1% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1031 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <0.5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1032 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <0.5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1033 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >1.5% of applied dose | Epidermis of human breast skin | 22890441 |
| 1034 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~2% of applied dose | Epidermis of human breast skin | 22890441 |
| 1035 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <4% of applied dose | Epidermis of human breast skin | 22890441 |
| 1036 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~0.5% of applied dose | Epidermis of human breast skin | 22890441 |
| 1037 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <1% of applied dose | Epidermis of human breast skin | 22890441 |
| 1038 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >8% of applied dose | Dermis of human breast skin | 22890441 |
| 1039 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <4% of applied dose | Dermis of human breast skin | 22890441 |
| 1040 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | <18% of applied dose | Dermis of human breast skin | 22890441 |
| 1041 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~3% of applied dose | Dermis of human breast skin | 22890441 |
| 1042 | β-Ala-H | L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >8% of applied dose | Dermis of human breast skin | 22890441 |
| 1043 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1044 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~6% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1045 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~1.5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1046 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~5% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1047 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~3% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1048 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~2% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1049 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~7% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1050 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~3% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1051 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | 2% of applied dose | Stratum corneum of human breast skin | 22890441 |
| 1052 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~11% of applied dose | Epidermis of human breast skin | 22890441 |
| 1053 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~9% of applied dose | Epidermis of human breast skin | 22890441 |
| 1054 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~3% of applied dose | Epidermis of human breast skin | 22890441 |
| 1055 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~10% of applied dose | Epidermis of human breast skin | 22890441 |
| 1056 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~7% of applied dose | Epidermis of human breast skin | 22890441 |
| 1057 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~5% of applied dose | Epidermis of human breast skin | 22890441 |
| 1058 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~12% of applied dose | Epidermis of human breast skin | 22890441 |
| 1059 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >4% of applied dose | Epidermis of human breast skin | 22890441 |
| 1060 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~4% of applied dose | Epidermis of human breast skin | 22890441 |
| 1061 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >36% of applied dose | Dermis of human breast skin | 22890441 |
| 1062 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | >26% of applied dose | Dermis of human breast skin | 22890441 |
| 1063 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~26% of applied dose | Dermis of human breast skin | 22890441 |
| 1064 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | 25% of applied dose | Dermis of human breast skin | 22890441 |
| 1065 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | 20% of applied dose | Dermis of human breast skin | 22890441 |
| 1066 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~20% of applied dose | Dermis of human breast skin | 22890441 |
| 1067 | β-Ala-H | N-acetyl- L -carnosine | Antioxidant | Franz diffusion cell, HPLC | ~26% of applied dose | Dermis of human breast skin | 22890441 |