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IDSequenceNameNature of peptide or cargoAssayTissue permeabilityTissue SamplePUBMED ID
1345pGlu-EDSGEpidermal pentapeptideIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.Significant mitotic rate inhibition initially and on day 7 after an overshoot on day 6Back skin of female hairless mice (hr/hr)1977237
1346pGlu-EDSGEpidermal pentapeptideIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.Initial increase in mitotic rate, peaking on day 2, from day 2 to day 10, mitotic rate was lower than normal.Back skin of female hairless mice (hr/hr)1977237
1347pGlu-EDSGEpidermal pentapeptideIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.The mitotic rate was strongly increased with peaks at days 1, 3 and 6 (twice the control value).Back skin of female hairless mice (hr/hr)1977237