A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1659 | Th1152 | Drotrecogin alfa | Heavy Chain: LIDGKMT Full view | 402 | Ib | Infectious | Xigris | Eli Lilly and Company | Sterile, lyophilized, white to off-white powder | Intravenous Infusion | Antisepsis | Coagulation factor VIII, V, Plasminogen activator inhibitor 1, Thrombomodulin, Vitamin K-dependent protein S, Ceruloplasmin, Prothrombin, Platelet factor 4, Plasma serine protease inhibitor, Serpin B6, Vitamin K-dependent gamma-carboxylase, Endothelial protein C receptor |
1780 | Th1188 | Hyaluronidase (Human Recombinant) | NA Full view | 0 | Ib | Adjunct therapy | NA | NA | NA | NA | NA | Hyaluronan; Transforming growth factor beta-1 |
1805 | Th1199 | Ramucirumab | ramucirumab|Homo sap Full view | 909 | IIIc | Cancer | Cyramza | Eli Lilly and Company | Solution | Intravenous | Antineoplastic and Immunomodulating Agents | Vascular endothelial growth factor receptor 2 |
1821 | Th1212 | Insulin Pork | A chain GIVEQCCTSICS Full view | 68 | Ia | Metabolic Disorders | Iletin II | Lilly | sterile suspension | Subcutaneous | Hypoglycemic Agents, Antidiabetic Agents | Insulin receptor, Insulin-like growth factor 1 receptor, Insulin-degrading enzyme, HLA class II histocompatibility antigen, DQ alpha 2 chain, HLA class II histocompatibility antigen, DQ beta 1 chain, Retinoblastoma-associated protein, Cathepsin D, Carboxypeptidase E, Neuroendocrine convertase 2, Neuroendocrine convertase 1, Protein NOV homolog, Low-density lipoprotein receptor-related protein 2, Insulin-like growth factor-binding protein 7, Synaptotagmin-like protein 4, Cytochrome P450 1A2 |
1831 | Th1221 | C1 Esterase Inhibitor (Recombinant) | NA Full view | 0 | IIa | Cardiac Disorders | Ruconest | Tjoapack Netherlands Bv | Powder and liquid for solution | Intravenous | Blood and Blood Forming Organs | Complement C1r subcomponent, Complement C1s subcomponent, Plasma kallikrein, Coagulation factor XII, Prothrombin, Coagulation factor XI, Tissue-type plasminogen activator |
1844 | Th1232 | Lenograstim | NA Full view | 0 | Ib | Immunological Disorders | Granocyte | NA | Solid | Subcutaneous or Intravenous | Antineoplastic and Immunomodulating Agents | Granulocyte colony-stimulating factor receptor |
1851 | Th1238 | Susoctocog alfa | AIRRYYLGAVELSWDYRQSE Full view | 1448 | Ib | Hematological Disorders | Obizur | NA | Powder and solvent for solution for injection. | Intravenous | Blood coagulation factors, Antihaemorrhagics | von Willebrand factor |
1852 | Th1239 | Thrombomodulin Alfa | NA Full view | 0 | Ib | Hematological Disorders | Recomodulin (in Japan only) | Asahi Kasei Pharma Corp | lyophilized powder for solution | Intravenous | Anticoagulant agent, Antiplatelet agent | Prothrombin, Coagulation factor V |