==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 58
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1005Th1002CetuximabHeavy chain:QVQLKQSG Full view243IIIcCancerErbituxImClone Systems IncSterile, clear, colorless liquid of pH 7.0-7.4, which may contain a small amount of easily visible, white, amorphous cetuximab particulatesIntravenous infusionAntineoplastic Agents Epidermal growth factor receptor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1028Th1005EtanerceptLPAQVAFTPYAPEPGSTCRL Full view255IIaImmunologicalEnbrelImmunex CorpLyophilized powder.Subcutaneous injectionImmunosuppressive Agents Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re
1029Th1005EtanerceptLPAQVAFTPYAPEPGSTCRL Full view255IIaImmunologicalEnbrel SureclickN.A.SolutionSubcutaneous injectionImmunosuppressive Agents Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re
1117Th1016PegfilgrastimMTPLGPASSLPQSFLLKCLE Full view175IbImmunologicalNeulastaAmgen Inc.SolutionSubcutaneous injectionImmunosuppressive Agents, Anti-neutropenic agents Granulocyte colony-stimulating factor receptor,Neutrophil elastase
1120Th1017SargramostimAPARSPSPSTQPWEHVNAIQ Full view127IbImmunologicalLeucomaxNovartisSolutionSubcutaneous and Intravenous infusionImmunosuppressive Agents Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan
1121Th1017SargramostimAPARSPSPSTQPWEHVNAIQ Full view127IbImmunologicalLeukineBerlex Laboratories IncSterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for InjectionSubcutaneous Injection (SC) or Intravenous infusion (IV)Immunosuppressive Agents Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1151Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHelixate FSN.A.Sterile, stable, purified, nonpyrogenic, dried concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1152Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHemofil MN.A.Dry concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1205Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalHumulin REli Lilly and CompanySterile, clear, aqueous, and colorless solutionSubcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision.Antidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1206Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalNovolin RNovo NordiskSterile, clear, aqueous, and colorless solutionSubcutaneous and Intravenous infusionAntidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1234Th1032Coagulation factor VIIaANAFLEELRPGSLERECKEE Full view255IbHematological,MetabolicNovoSevenNovo NordiskSterile, white lyophilized powderInjectionThrombotic Agents, Coagulants Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor
1246Th1034PaliferminSYDYMEGGDIRVRRLFCRTQ Full view140IbCancerKepivanceAmgen IncSterile, lyophilized powderIntravenous infusionAnti-Mucositis Agents Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein
1275Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalogEli LillySterile, aqueous, clear, and colorless solutionSubcutaneous and Intravenous infusionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1276Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog KwikPenEli LillySolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1277Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog PenEli LillyN.A.N.A.Hypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1283Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantusSanofi-AventisSolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1284Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus OptiSetN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1285Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus SoloStarN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1316Th1044AdalimumabLight-chain:DIQMTQS< Full view230IcImmunologicalHumiraAbbott LaboratoriesSterile, preservative-free solutionSubcutaneous administrationImmunosuppressive Agents, Anti-inflammatory, Antirheumatic agents Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm
1317Th1044AdalimumabLight-chain:DIQMTQS< Full view230IcOsteologicalHumira PenAbbott LaboratoriesSterile, preservative-free solutionSubcutaneous injectionImmunosuppressive Agents, Anti-inflammatory, Antirheumatic agents Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm
1358Th1050Pegademase bovineMAQTPAFNKPKVELHVHLDG Full view255IaMetabolicAdagenEnzon Inc.Isotonic, pyrogen free, sterile solution, pH 7.2-7.4Intramusular InjectionEnzyme Replacement Agents Adenosine,Growth factor receptor-bound protein 2
1368Th1054InfliximabN.A.
Full view
0IIaImmunologicalREMICADECentocor IncSterile, white, lyophilized powder, following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2.Intravenous infusionAntirheumatic Agents, Anti-Inflammatory Agents, Non-Steroidal, Dermatologic Agents, Gastrointestinal Agents and Immunosuppressive Agents Tumor necrosis factor
1382Th1060Insulin, porcineA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicvetsulinIntervet Inc (Merck Animal Health)Sterile injectable suspension in multidose vials containing 10 mL of 40 IU/mL porcine insulin zinc suspensionSubcutaneous InjectionHypoglycemic Agents Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Hyaluronan, Transforming growth factor beta-1
1385Th1061TrastuzumabLight chain 1: DIQMT Full view1364IIaCancerHerceptinGenentechSterile, white to pale yellow, preservative-free lyophilized powder Intravenous administrationAntineoplastic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Insulin-degrading enzyme,HLA class II histocompatibility antigen, DQ alpha 2 chain,HLA class II histocompatibility antigen, DQ beta 1 chain,Retinoblastoma-associated protein,Cathepsin D,Carboxypeptidase E,Neuroendocrine convertase 2,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-related protein 2,Insulin-like growth factor-binding protein 7,Synaptotagmin-like protein 4
1389Th1062RituximabHeavy Chain: QVQLQQP Full view664IIaCancer/ImmunologicalRituxanBiogen Idec Inc., and Genentech USA, IncSterile, clear, colorless, preservative-free liquid concentrate Intravenous administrationAntineoplastic Agents, Immunologic Factors and Antirheumatic Agents B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Receptor tyrosine-protein kinase erbB-2,Epidermal growth factor receptor,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor I
1456Th1086Interferon Alfa-2B, RecombinantCDLPQTHSLGSRRTLMLLAQ Full view165IbImmunologicalINTRON® AMerckPowder or solutionIntramuscular, Subcutaneous, Intralesional, or Intravenous injectionImmunosuppressive Agents Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin
1470Th1092ArcitumomabHeavy chain 1EVKLVES Full view1310IIbCancerCEA-ScanN.A.N.A.N.A.Diagnostic Agents Vascular endothelial growth factor A,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Carcinoembryonic antigen-related cell adhesion molecule 1
1474Th1094PanitumumabN.A. Full view0IIaCancerVectibixAmgen IncSterile, colorless, pH 5.6 to 6.0 liquid for intravenous (IV) infusion, which may contain a small amount of visible translucent-to-white, amorphous, proteinaceous, panitumumab particulatesN.A.N.A. Epidermal growth factor receptor
1475Th1095RanibizumabLight Chain SASQDISN Full view447IIaHematological/Eye DisorderLucentisGenentechSterile, colorless to pale yellow solutionIntravitreal injectionOphthalmics Vascular endothelial growth factor A
1480Th1099MecaserminGPETLCGAELVDALQFVCGD Full view70IbHormonalN.A.N.A.N.A.N.A.N.A. Insulin-like growth factor 1 receptor,Insulin-like growth factor-binding protein 3,Insulin receptor,Cation-independent mannose-6-phosphate receptor
1549Th1118SulodexideN.A. Full view0IIIcHormonal/genetic/Hematological/N.A.SULODEXIDESyntex S.AN.A.N.A.Antithrombins and Fibrinolytic Agents and Hypoglycemic Agents and Anticoagulants and Hypolipidemic Agents Heparin cofactor 2,Antithrombin-III
1570Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalXgevaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1571Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalProliaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1583Th1125GolimumabN.A. Full view0IIbImmunologicalSimponi InjectionN.A.Clear to slightly opalescent, colorless to light yellow solutionSubcutaneous injectionAntipsoriatic Agents and Monoclonal antibodies and TNF inhibitor Tumor necrosis factor
1584Th1125GolimumabN.A. Full view0IIbImmunologicalSimponi InjectionN.A.Sterile concentrated solution of the golimumab antibodyIntravenous infusionAntipsoriatic Agents and Monoclonal antibodies and TNF inhibitor Tumor necrosis factor
1604Th1130Brentuximab VedotinHeavy chain:QIQLQQSG Full view664IIbCancerAdcetrisSeattle GeneticsSterile, white to off-white, preservative-free lyophilized cake or powder in single-use vials.Intravenous infusionN.A. Tumor necrosis factor receptor superfamily member 8
1609Th1132BelimumabN.A. Full view0IIaImmunologicalBenlystaGlaxoSmithKlineSterile, white to off-white, preservative-free, lyophilized powderIntravenous infusionMonoclonal antibodies Tumor necrosis factor ligand superfamily member 13B
1615Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerEyleaRegeneron PharmaceuticalsSterile, clear, and colorless to pale yellow solution.Intravitreal injectionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1616Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerZaltrapSanofi and Regeneron Pharmaceuticals, Inc.Sterile, clear, colorless to pale yellow, non-pyrogenic, preservative-free, solution.Intravenous infusionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1628Th1139Certolizumab PegolLight chain: DIQMTQS Full view443IIbImmunologcalCimziaUCBSterile, white, lyophilized powder for solution or as a sterile, solution in a single-use prefilled 1 mL glass syringeSubcutaneous injectionTNF inhibitor Tumor necrosis factor