==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 48
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1055Th1009AlteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicActivaseGenentech IncSterile, white to off-white, lyophilized powderIntravenousThrombolytic Agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1067Th1012ReteplaseSYQGNSDCYFGNGSAYRGTH Full view255IbHematological,MetabolicRetavaseCentocorSterile, white, lyophilized powderIntravenous InjectionFibrinolytic Agents, Thrombolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1117Th1016PegfilgrastimMTPLGPASSLPQSFLLKCLE Full view175IbImmunologicalNeulastaAmgen Inc.SolutionSubcutaneous injectionImmunosuppressive Agents, Anti-neutropenic agents Granulocyte colony-stimulating factor receptor,Neutrophil elastase
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1151Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHelixate FSN.A.Sterile, stable, purified, nonpyrogenic, dried concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1152Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHemofil MN.A.Dry concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1201Th1026AnistreplaseSYQVICRDEKTQMIYQQHQS Full view255IcHematological,MetabolicEminaseWulfing Pharma GmbHDry powderIntravenous infusionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1205Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalHumulin REli Lilly and CompanySterile, clear, aqueous, and colorless solutionSubcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision.Antidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1206Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalNovolin RNovo NordiskSterile, clear, aqueous, and colorless solutionSubcutaneous and Intravenous infusionAntidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1210Th1028TenecteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicTNKaseGenentech IncSterile, white to off-white, lyophilized powderIntravenous InjectionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein
1234Th1032Coagulation factor VIIaANAFLEELRPGSLERECKEE Full view255IbHematological,MetabolicNovoSevenNovo NordiskSterile, white lyophilized powderInjectionThrombotic Agents, Coagulants Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor
1246Th1034PaliferminSYDYMEGGDIRVRRLFCRTQ Full view140IbCancerKepivanceAmgen IncSterile, lyophilized powderIntravenous infusionAnti-Mucositis Agents Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein
1331Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryAralastBaxterLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1332Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryProlastinTalecris Biotherapeutics C formerly BayerLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1385Th1061TrastuzumabLight chain 1: DIQMT Full view1364IIaCancerHerceptinGenentechSterile, white to pale yellow, preservative-free lyophilized powder Intravenous administrationAntineoplastic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Insulin-degrading enzyme,HLA class II histocompatibility antigen, DQ alpha 2 chain,HLA class II histocompatibility antigen, DQ beta 1 chain,Retinoblastoma-associated protein,Cathepsin D,Carboxypeptidase E,Neuroendocrine convertase 2,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-related protein 2,Insulin-like growth factor-binding protein 7,Synaptotagmin-like protein 4
1389Th1062RituximabHeavy Chain: QVQLQQP Full view664IIaCancer/ImmunologicalRituxanBiogen Idec Inc., and Genentech USA, IncSterile, clear, colorless, preservative-free liquid concentrate Intravenous administrationAntineoplastic Agents, Immunologic Factors and Antirheumatic Agents B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Receptor tyrosine-protein kinase erbB-2,Epidermal growth factor receptor,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor I
1434Th1074AlgluceraseARPCIPKSFGYSSVVCVCNA Full view497IaMetabolicCeredaseGenzyme CorporationClear sterile non-pyrogenic solution of alglucerase in a citrate buffered solutionIntravenous injectionEnzyme Replacement Agents Plasminogen,Proteinase-activated receptor 1
1439Th1077UrofollitropinAlpha chain:APDVQDCP Full view203IbHormonalBRAVELLEFerring Pharmaceuticals Inc.Sterile, lyophilized powder used after reconstitution with sterile 0.9% Sodium Chloride InjectionIntramuscular and Subcutaneous administration Fertility Agents Glutamate carboxypeptidase 2
1440Th1077UrofollitropinAlpha chain:APDVQDCP Full view203IbHormonalMetrodinN.A.Sterile, lypholized form contains an acidic, water soluble glycoprotein biologically standardized for FSH gonadotropin activityIntramuscular injection.Fertility Agents Glutamate carboxypeptidase 2
1441Th1077UrofollitropinAlpha chain:APDVQDCP Full view203IbHormonalFertinexN.A.Sterile, lyophilized form contains an acidic, water soluble glycoprotein biologically standardized for FSH gonadotropin activitySubcutaneous injection.Fertility Agents Glutamate carboxypeptidase 2
1456Th1086Interferon Alfa-2B, RecombinantCDLPQTHSLGSRRTLMLLAQ Full view165IbImmunologicalINTRON® AMerckPowder or solutionIntramuscular, Subcutaneous, Intralesional, or Intravenous injectionImmunosuppressive Agents Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin
1560Th1121Pertuzumablight chain DIQMTQSP Full view664IIIcCancerPerjetaGenentechSterile, clear to slightly opalescent, colorless to pale brown liquidIntravenous infusionMonoclonal antibodies Receptor tyrosine-protein kinase erbB-2
1602Th1128Velaglucerase AlfaARPCIPKSFGYSSVVCVCNA Full view497IaHormonalVPRIVShireSterile, preservative free, lyophilized powderIntravenous infusionEnzymes Glucosylceramidase
1659Th1152Drotrecogin alfaHeavy Chain: LIDGKMT Full view402IbInfectiousXigrisEli Lilly and CompanySterile, lyophilized, white to off-white powderIntravenous InfusionAntisepsis Coagulation factor VIII, V, Plasminogen activator inhibitor 1, Thrombomodulin, Vitamin K-dependent protein S, Ceruloplasmin, Prothrombin, Platelet factor 4, Plasma serine protease inhibitor, Serpin B6, Vitamin K-dependent gamma-carboxylase, Endothelial protein C receptor
1663Th1155UrokinaseKPSSPPEELKFQCGQKTLRP Full view276IbHaemetologicalKinlyticN.A.Sterile lyophilized white powderIntravenous infusionN.A. Plasminogen,Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, Tissue-type plasminogen activator, Plasminogen activator inhibitor 1, 2, Plasma serine protease inhibitor, Low-density lipoprotein receptor-related protein 2, Suppressor of tumorigenicity 14 protein, Nidogen-1
1678Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis U.S. LlcInjection, SolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 9
1679Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis Canada IncSolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 10
1680Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis Canada IncSolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 11
1681Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis U.S. LlcInjection, SolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 14
1715Th1171C1 Esterase Inhibitor (Human)NA Full view0IaGenetic DisordersBerinert 1500Csl Behring Canada Inckit; Powder for SolutionIntravenousNA Plasma protease C1 inhibitor
1717Th1171C1 Esterase Inhibitor (Human)NA Full view0IaGenetic DisordersCinryzeViropharma Biologics IncPowder for SolutionIntravenousNA Plasma protease C1 inhibitor
1724Th1174DaratumumabNA Full view0IIIcCancerDarzalexJanssen Biotech, Inc.Solution, concentrateIntravenousAntineoplastic Agents ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
1736Th1177Elosulfase alfaAPQPPNILLLLMDDMGWGDL Full view496IaMetabolic DisordersVimizimBiomarin International LimitedSolutionIntravenousEnzymes; Alimentary Tract and Metabolism N-acetylgalactosamine-6-sulfatase
1741Th1179EvolocumabNA Full view0IIaGenetic/Metabolic/CardiacNANAInjection, Solution; InjectionSubcutaneousLipid Modifying Agents, Plain; Cardiovascular System Proprotein convertase subtilisin/kexin type 9
1742Th1179EvolocumabNA Full view0IIaGenetic/Metabolic/CardiacRepathaAmgen IncInjection, SolutionSubcutaneousLipid Modifying Agents, Plain; Cardiovascular System Proprotein convertase subtilisin/kexin type 10
1743Th1179EvolocumabNA Full view0IIaGenetic/Metabolic/CardiacRepathaAmgen Canada IncSolutionSubcutaneousLipid Modifying Agents, Plain; Cardiovascular System Proprotein convertase subtilisin/kexin type 11
1744Th1179EvolocumabNA Full view0IIaGenetic/Metabolic/CardiacRepathaAmgen IncInjection, SolutionSubcutaneousLipid Modifying Agents, Plain; Cardiovascular System Proprotein convertase subtilisin/kexin type 12
1821Th1212Insulin PorkA chain GIVEQCCTSICS Full view68IaMetabolic DisordersIletin IILillysterile suspensionSubcutaneousHypoglycemic Agents, Antidiabetic Agents Insulin receptor, Insulin-like growth factor 1 receptor, Insulin-degrading enzyme, HLA class II histocompatibility antigen, DQ alpha 2 chain, HLA class II histocompatibility antigen, DQ beta 1 chain, Retinoblastoma-associated protein, Cathepsin D, Carboxypeptidase E, Neuroendocrine convertase 2, Neuroendocrine convertase 1, Protein NOV homolog, Low-density lipoprotein receptor-related protein 2, Insulin-like growth factor-binding protein 7, Synaptotagmin-like protein 4, Cytochrome P450 1A2
1848Th1236Sipuleucel-TNA Full view0IIIcCancerProvengeNASolutionIntravenousAntineoplastic and Immunomodulating Agents Prostatic acid phosphatase