==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 158
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1001Th1001LepirudinLVYTDCTESGQNLCLCEGSN Full view65IaHematological,MetabolicRefludanBerlex LabsSterile, white, freeze-dried powderIntravenous infusionAntithrombins and Fibrinolytic Agents Prothrombin
1005Th1002CetuximabHeavy chain:QVQLKQSG Full view243IIIcCancerErbituxImClone Systems IncSterile, clear, colorless liquid of pH 7.0-7.4, which may contain a small amount of easily visible, white, amorphous cetuximab particulatesIntravenous infusionAntineoplastic Agents Epidermal growth factor receptor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1025Th1004Denileukin diftitoxMGADDVVDSSKSFVMENFSS Full view255IIbCancerOntakSeragen IncSterile, white, preservative-free, lyophilized powder.Intravenous(IV) administrationAntineoplastic Agents Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Cytokine receptor common subunit gamma
1032Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngiomaxMedicines Co or MDCOWhite lyophilized cake in single-use vialsIntravenous infusionAntithrombins Prothrombin
1055Th1009AlteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicActivaseGenentech IncSterile, white to off-white, lyophilized powderIntravenousThrombolytic Agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1064Th1011Darbepoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalAranespAmgen IncSterile, colorless, preservative-free solution containing polysorbateIntravenousor Subcutaneous administrationAnti-anemic Agents, Hematinics Erythropoietin receptor
1067Th1012ReteplaseSYQGNSDCYFGNGSAYRGTH Full view255IbHematological,MetabolicRetavaseCentocorSterile, white, lyophilized powderIntravenous InjectionFibrinolytic Agents, Thrombolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1071Th1013Epoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalBinocritSandozClear colourless solutionSubcutaneous and Intravenous infusionAnti-anemic Agents, Hematinics Erythropoietin receptor
1075Th1013Epoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalEpoginChugaiN.A.Subcutaneous or by Intravenous.Anti-anemic Agents, Hematinics Erythropoietin receptor
1076Th1013Epoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalEprexJanssen-Cilag. Ortho Biologics LLCSolutionSubcutaneous and Intravenous infusionAnti-anemic Agents, Hematinics Erythropoietin receptor
1078Th1013Epoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalProcritOrtho BiotechSterile, colorless liquid in an isotonic sodium chloride/sodium citrate buffered solution or a sodium chloride/sodium phosphate buffered solutionIntravenous(IV) or Subcutaneous (SC) administration.Anti-anemic Agents, Hematinics Erythropoietin receptor
1120Th1017SargramostimAPARSPSPSTQPWEHVNAIQ Full view127IbImmunologicalLeucomaxNovartisSolutionSubcutaneous and Intravenous infusionImmunosuppressive Agents Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan
1121Th1017SargramostimAPARSPSPSTQPWEHVNAIQ Full view127IbImmunologicalLeukineBerlex Laboratories IncSterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for InjectionSubcutaneous Injection (SC) or Intravenous infusion (IV)Immunosuppressive Agents Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan
1129Th1018SecretinHSDGTFTSELSRLRDSARLQ Full view27IVHormonal disordersSecreFloRepligen CorpLyophilized white powderIntravenous infusionDiagnostic Agents Secretin receptor
1130Th1018SecretinHSDGTFTSELSRLRDSARLQ Full view27IVHormonal disordersSecremaxRepligen CorpSolutionIntravenousDiagnostic Agents Secretin receptor
1142Th1020AsparaginaseQMSLQQELRYIEALSAIVET Full view255IcCancerElsparMerck & Co. IncLyophilized plug or powderIntravenous or Intramuscular. Intravenous method dose has higher risk of allergic reaction, so often a test dose is given first.Antineoplastic Agents L-asparagine
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1151Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHelixate FSN.A.Sterile, stable, purified, nonpyrogenic, dried concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1152Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHemofil MN.A.Dry concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1194Th1025Intravenous ImmunoglobulinIGG1:PSALTQPPSASGSLG Full view250IaImmunologicalFlebogammaInstituto Grifols SASterile, clear or slightly opalescent and colorless to pale yellow, liquidIntravenous infusionImmunosuppressive Agents, Immunologic factors, Anti-infective agents High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg
1195Th1025Intravenous ImmunoglobulinIGG1:PSALTQPPSASGSLG Full view250IaImmunologicalGamunexTalecris BiotherapeuticsSterile solutionIntravenous infusionImmunosuppressive Agents, Immunologic factors, Anti-infective agents High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg
1201Th1026AnistreplaseSYQVICRDEKTQMIYQQHQS Full view255IcHematological,MetabolicEminaseWulfing Pharma GmbHDry powderIntravenous infusionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1205Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalHumulin REli Lilly and CompanySterile, clear, aqueous, and colorless solutionSubcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision.Antidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1206Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalNovolin RNovo NordiskSterile, clear, aqueous, and colorless solutionSubcutaneous and Intravenous infusionAntidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1210Th1028TenecteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicTNKaseGenentech IncSterile, white to off-white, lyophilized powderIntravenous InjectionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein
1246Th1034PaliferminSYDYMEGGDIRVRRLFCRTQ Full view140IbCancerKepivanceAmgen IncSterile, lyophilized powderIntravenous infusionAnti-Mucositis Agents Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein
1252Th1035Glucagon recombinantHSQGTFTSDYSKYLDSRRAQ Full view29IVHormonal/Metabolic/geneticGlucaGenNovo NordiskSterile, lyophilized white powderSubcutaneous, Intramuscular, or Intravenous infusionHypoglycemic Agents Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor
1257Th1036AldesleukinMAPTSSSTKKTQLQLEHLLL Full view134IbCancer/InfectiousProleukinChiron CorpSterile, white to off-white, lyophilized cakeIntravenous administrationAntineoplastic Agents, Anti-HIV agents Interleukin-2 receptor subunit beta,Interleukin-2 receptor subunit alpha,Cytokine receptor common subunit gamma
1275Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalogEli LillySterile, aqueous, clear, and colorless solutionSubcutaneous and Intravenous infusionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1305Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticElitekSanofi-Synthelabo IncSterile, white to off-white, lyophilized powderIntravenous administrationAntihyperuricemic Agents, Gout suppressants Uric acid
1306Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticFasturtecN.A.Powder and solvent that are made upto make solution.Intravenous administartionAntihyperuricemic Agents, Gout suppressants Uric acid
1324Th1045ImigluceraseARPCIPKSFGYSSVVCVCNA Full view255IaMetabolicCerezymeGenzymeSterile, non-pyrogenic, white to off-white lyophilized productIntravenous infusionEnzyme Replacement Agents Glucocerebroside
1327Th1046AbciximabH ReoPro-like antibo Full view218IIaGenetic/Metabolic/HaemetologicalReoProEli Lilly and CompanyClear, colorless, sterile, non-pyrogenic solutionIntravenous administartionPlatelet Aggregation Inhibitors, Anticoagulants Integrin beta-3,Integrin alpha-IIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immuno
1331Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryAralastBaxterLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1332Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryProlastinTalecris Biotherapeutics C formerly BayerLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1337Th1048PegaspargaseMEFFKKTALAALVMGFSGAA Full view255IcCancerOncasparEnzon IncSolutionIntravenous or Intramuscular administrationAntineoplastic Agents L-asparagine
1361Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuminarCSL BehringSterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process.Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route.Serum substitutes N.A.
1362Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuteinGRIFOLSSterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume).Albutein 20% is to be administered by the Intravenous route.Serum substitutes N.A.
1363Th1052EptifibatideMpr-Har-Gly-Asp-Trp- Full view7IbHematological/MetabolicINTEGRILINSchering-Plough/EssexClear, colorless, sterile, non-pyrogenic solution  of EptifibatideInjection Solution for IIntravenousUsePlatelet Aggregation Inhibitors Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor
1365Th1053Serum albumin iodonatedMKWVTFISLLFLFSSAYSRG Full view600IVHematological DisordersMegatopeIsoTex DiagnosticsColorless to very pale yellow solutionsInjection for Intravenous administrationDiagnostic Agents Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP
1366Th1053Serum albumin iodonatedMKWVTFISLLFLFSSAYSRG Full view600IVHematological DisordersJeanotopeIsoTex DiagnosticsSterile, nonpyrogenic, aqueos solutionIntravenous infusionDiagnostic Agents Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP