A database of FDA approved therapeutic peptides and proteins
| ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1028 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel | Immunex Corp | Lyophilized powder. | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
| 1029 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel Sureclick | N.A. | Solution | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
| 1049 | Th1008 | Peginterferon alfa-2a | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Pegasys | Hoffman-La Roche Inc | Sterile, preservative-free, colorless to light yellow injectable solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1059 | Th1010 | Interferon alfa-n1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Infectious /Immunological | Wellferon | GlaxoSmithKline | Solution | Injection | Antiviral Agents, Immunologic factors, Immunosuppressiv agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1110 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon | Interferon Sciences Inc. | Solution | Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1111 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon LDO | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1112 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon N Injection | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1117 | Th1016 | Pegfilgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | Neulasta | Amgen Inc. | Solution | Subcutaneous injection | Immunosuppressive Agents, Anti-neutropenic agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase |
| 1120 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leucomax | Novartis | Solution | Subcutaneous and Intravenous infusion | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
| 1121 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leukine | Berlex Laboratories Inc | Sterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for Injection | Subcutaneous Injection (SC) or Intravenous infusion (IV) | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
| 1135 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | PEG-Intron | Schering Corp | Powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1136 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Unitron PEG | N.A. | Lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1180 | Th1023 | Anakinra | MRPSGRKSSKMQAFRIWDVN Full view | 153 | IIa | Immunological | Kineret | Amgen Inc | Sterile, clear, colorless-to-white, preservative free solution | Subcutaneous (SC) administration | Immunosuppressive Agents, Anti-rheumatic agents | Interleukin-1 receptor type 1 |
| 1193 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Civacir | N.A. | N.A. | N.A. | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
| 1194 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Flebogamma | Instituto Grifols SA | Sterile, clear or slightly opalescent and colorless to pale yellow, liquid | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
| 1195 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Gamunex | Talecris Biotherapeutics | Sterile solution | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
| 1226 | Th1030 | Interferon gamma-1b | CYCQDPYVKEAENLKKYFNA Full view | 146 | Ib | Immunological | Actimmune | InterMune Inc | Sterile, clear, colorless solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon gamma receptor 1,Interferon gamma receptor 2 |
| 1229 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Roferon A | Hoffmann-La Roche Inc | Solution | Subcutaneous Injection | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1230 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Veldona | Amarillo Biosciences | N.A. | N.A. | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1265 | Th1038 | Omalizumab | Heavy chain:EVQLVESG Full view | 243 | IIa | Immunological | Xolair | Genentech Inc | Sterile, white, preservative free, lyophilized powde | Subcutaneous Injection | Anti-Allergic Agents, Anti-asthmatic, Immuno-suppressive agents | High affinity immunoglobulin epsilon receptor subunit alpha and beta |
| 1316 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Immunological | Humira | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous administration | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
| 1341 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Avonex | Biogen Inc | Lyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector. | Intramuscular Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1342 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1343 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaseron | Merck | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1344 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Blastoferon | Sidus | N.A. | N.A. | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1345 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1346 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Rebif | Merck | Sterile solution in a prefilled syringe or REBIF Rebidose autoinjector | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1368 | Th1054 | Infliximab | N.A. Full view | 0 | IIa | Immunological | REMICADE | Centocor Inc | Sterile, white, lyophilized powder, following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2. | Intravenous infusion | Antirheumatic Agents, Anti-Inflammatory Agents, Non-Steroidal, Dermatologic Agents, Gastrointestinal Agents and Immunosuppressive Agents | Tumor necrosis factor |
| 1376 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaseron | Bayer | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1377 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1378 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1379 | Th1058 | Interferon alfacon-1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological/Infectious | INFERGEN | Kadmon Pharmaceuticals, LLC. | Sterile, clear, colorless, preservative-free liquid | Subcutaneous Injection | Antiviral Agents and Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1389 | Th1062 | Rituximab | Heavy Chain: QVQLQQP Full view | 664 | IIa | Cancer/Immunological | Rituxan | Biogen Idec Inc., and Genentech USA, Inc | Sterile, clear, colorless, preservative-free liquid concentrate |  Intravenous administration | Antineoplastic Agents, Immunologic Factors and Antirheumatic Agents | B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Receptor tyrosine-protein kinase erbB-2,Epidermal growth factor receptor,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor I |
| 1398 | Th1063 | Basiliximab | Heavy Chain: QLQQSGT Full view | 657 | IIa | Immunological | Simulect | Novartis | Sterile lyophilisate which is available in 6 mL colorless glass vials and is available in 10 mg and 20 mg strength | intravenous infusion mainly or bolus (if no allergic reactions occurs) | Immunosuppressive Agents | N.A. |
| 1400 | Th1064 | Muromonab | Heavy Chain: QVQLQQS Full view | 664 | IIa | Immunological | ORTHOCLONE OKT3 STERILE SOLUTION | Centocor Ortho Biotech, L.P. | Sterile Solution is a murine monoclonal antibody to the CD3 antigen of human T cells which functions as an immunosuppressant. | For Intravenous Use Only | Immunologic Factors and Immunosuppressive Agents | N.A. |
| 1442 | Th1078 | Efalizumab | Light Chain:DIQMTQSP Full view | 229 | IIa | Immunological | RAPTIVA | Genentech, Inc. | Sterile, white to off-white, lyophilized powder in single-use glass vials | Subcutaneous injection. | Immunosuppressive Agents | Iduronic acid |
| 1449 | Th1081 | Antithymocyte Globulin | N.A. Full view | 0 | IIa | Immunological | Antithymocyte globulin | Pfizer | N.A. | Intravenous infusion | Immunologic Factors and Immunosuppressive Agents | N.A. |
| 1451 | Th1082 | Filgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | N.A. | N.A. | N.A. | N.A. | Immunosuppressive Agents, Antineutropenic Agents and Hematopoietic Agents | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
| 1456 | Th1086 | Interferon Alfa-2B, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | INTRON® A | Merck | Powder or solution | Intramuscular, Subcutaneous, Intralesional, or Intravenous injection | Immunosuppressive Agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin |
| 1466 | Th1090 | Daclizumab | QVQLVQSGAEVKKPGSSVKV Full view | 674 | IIa | Immunologicals | Zenapax | Roche | Clear, sterile, colorless concentrate for further dilution and intravenous administration | Intravenous injection | Immunosuppressive Agents | Fusion glycoprotein F0,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
| 1495 | Th1102 | Abatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | ORENCIA | Bristol-Myers Squibb | Lyophilized powder, supplied as a sterile, white, preservative-free, lyophilized powder for intravenous administration | Intravenous infusion and Subcutaneous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD80,T-lymphocyte activation antigen CD86 |
| 1531 | Th1110 | Thymalfasin | SDAAVDTSSEITTKDLKEKK Full view | 28 | Ib | Infectious/Immunological | Zadaxin | SciClone Pharmaceuticals (SCLN) | N.A. | Subcutaneous injection | N.A. | N.A. |
| 1532 | Th1111 | Defibrotide | N.A. Full view | 0 | Ib | Immunological | Noravid | sanofi-aventis | N.A. | N.A. | Antithrombins | Adenosine receptor A1,Adenosine receptor A2a,Adenosine receptor A2b |
| 1537 | Th1116 | Canakinumab | H-GAMMA-1 (VH(1-118) Full view | 842 | IIIb | Immunological | ILARIS | Novartis Pharmaceuticals | White, preservative-free, lyophilized powder | Subcutaneous injection | Anti-Inflammatory Agents and Monoclonal antibodies | Interleukin-1 beta |
| 1550 | Th1119 | Tocilizumab | N.A. Full view | 0 | IIa | Immunological | ACTEMRA | Genentech | Sterile, preservative-free solution, colorless to pale yellow liquid, with a pH of about 6.5 | Intravenous infusion, Subcutaneous injection | N.A. | Interleukin-6 receptor subunit alpha |
| 1562 | Th1122 | Rilonacept | rilonacept|Homo sapi Full view | 880 | IIa | Immunological | Arcalyst | Regeneron Pharmaceuticals | Sterile, white to off-white, lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interleukin-1 beta,Interleukin-1 alpha,Interleukin-1 receptor antagonist protein |
| 1583 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Clear to slightly opalescent, colorless to light yellow solution | Subcutaneous injection | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
| 1584 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Sterile concentrated solution of the golimumab antibody | Intravenous infusion | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
| 1596 | Th1126 | Belatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | Nulojix | Bristol-Myers Squibb | Sterile, white or off-white lyophilized powder | Intravenous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD86,T-lymphocyte activation antigen CD80 |
| 1609 | Th1132 | Belimumab | N.A. Full view | 0 | IIa | Immunological | Benlysta | GlaxoSmithKline | Sterile, white to off-white, preservative-free, lyophilized powder | Intravenous infusion | Monoclonal antibodies | Tumor necrosis factor ligand superfamily member 13B |