==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 94
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1001Th1001LepirudinLVYTDCTESGQNLCLCEGSN Full view65IaHematological,MetabolicRefludanBerlex LabsSterile, white, freeze-dried powderIntravenous infusionAntithrombins and Fibrinolytic Agents Prothrombin
1032Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngiomaxMedicines Co or MDCOWhite lyophilized cake in single-use vialsIntravenous infusionAntithrombins Prothrombin
1033Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngioxThe Medicines Company UK LtdPowder for concentrate for solutionInjectionAntithrombins Prothrombin
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1151Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHelixate FSN.A.Sterile, stable, purified, nonpyrogenic, dried concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1152Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHemofil MN.A.Dry concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1193Th1025Intravenous ImmunoglobulinIGG1:PSALTQPPSASGSLG Full view250IaImmunologicalCivacirN.A.N.A.N.A.Immunosuppressive Agents, Immunologic factors, Anti-infective agents High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg
1194Th1025Intravenous ImmunoglobulinIGG1:PSALTQPPSASGSLG Full view250IaImmunologicalFlebogammaInstituto Grifols SASterile, clear or slightly opalescent and colorless to pale yellow, liquidIntravenous infusionImmunosuppressive Agents, Immunologic factors, Anti-infective agents High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg
1195Th1025Intravenous ImmunoglobulinIGG1:PSALTQPPSASGSLG Full view250IaImmunologicalGamunexTalecris BiotherapeuticsSterile solutionIntravenous infusionImmunosuppressive Agents, Immunologic factors, Anti-infective agents High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg
1205Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalHumulin REli Lilly and CompanySterile, clear, aqueous, and colorless solutionSubcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision.Antidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1206Th1027Insulin RegularA-chain:GIVEQCCTSIC< Full view51IaGenetic/HormonalNovolin RNovo NordiskSterile, clear, aqueous, and colorless solutionSubcutaneous and Intravenous infusionAntidiabetic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r
1275Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalogEli LillySterile, aqueous, clear, and colorless solutionSubcutaneous and Intravenous infusionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1276Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog KwikPenEli LillySolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1277Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog PenEli LillyN.A.N.A.Hypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1283Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantusSanofi-AventisSolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1284Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus OptiSetN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1285Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus SoloStarN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1324Th1045ImigluceraseARPCIPKSFGYSSVVCVCNA Full view255IaMetabolicCerezymeGenzymeSterile, non-pyrogenic, white to off-white lyophilized productIntravenous infusionEnzyme Replacement Agents Glucocerebroside
1358Th1050Pegademase bovineMAQTPAFNKPKVELHVHLDG Full view255IaMetabolicAdagenEnzon Inc.Isotonic, pyrogen free, sterile solution, pH 7.2-7.4Intramusular InjectionEnzyme Replacement Agents Adenosine,Growth factor receptor-bound protein 2
1361Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuminarCSL BehringSterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process.Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route.Serum substitutes N.A.
1362Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuteinGRIFOLSSterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume).Albutein 20% is to be administered by the Intravenous route.Serum substitutes N.A.
1382Th1060Insulin, porcineA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicvetsulinIntervet Inc (Merck Animal Health)Sterile injectable suspension in multidose vials containing 10 mL of 40 IU/mL porcine insulin zinc suspensionSubcutaneous InjectionHypoglycemic Agents Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Hyaluronan, Transforming growth factor beta-1
1422Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/PancrecarbDigestive care US, Inc.Delayed-Release Capsules, Buffered and Enteric-Coated Microspheres.Oral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1423Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ViokaceAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble in alcohol and converted to tablet formOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1424Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ULTRESAAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether and converted to Delayed-Release CapsulesOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1425Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/PERTZYEDigestive care US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether PERTZYE delayed-release capsuleOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1426Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ULTRASEAxcan PharmaCapsules Enteric-Coated MicrospheresOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1427Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ZENPEPAptalis Pharma US, Inc.Delayed-Release CapsulesOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1434Th1074AlgluceraseARPCIPKSFGYSSVVCVCNA Full view497IaMetabolicCeredaseGenzyme CorporationClear sterile non-pyrogenic solution of alglucerase in a citrate buffered solutionIntravenous injectionEnzyme Replacement Agents Plasminogen,Proteinase-activated receptor 1
1437Th1076LaronidaseAPHLVQVDAARALWPLRRFW Full view626IaMetabolicALDURAZYMEGenzyme CorporationSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted prior to administration in 0.9% Sodium Chloride InjectionIntravenous infusionEnzyme Replacement Agents N.A.
1453Th1083Coagulation Factor IxYNSGKLEEFVQGNLERECME Full view415IaHematological/Metabolic/geneticAlprolixBiogen Idec Inc., and Genentech USA, IncSterile, non-pyrogenic, preservative-free, white to off-white, lyophilized powder to cake for reconstitution with the provided diluentIntravenous infusionCoagulants and Thrombotic Agents N.A.
1455Th1085Agalsidase BetaLDNGLARTPTMGWLHWERFM Full view398IaMetabolicFabrazymeGenzyme CorpSterile, nonpyrogenic, white to off-white, lyophilized cake or powder for reconstitution with Sterile Water for InjectionN.A.Enzyme Replacement Agents N.A.
1473Th1093EculizumabN.A. Full view0IaHaemetologicalSolirisAlexion, IncSterile, clear, colorless, preservative-free 10 mg/mL solution for intravenous infusionN.A.N.A. Complement C5
1476Th1096IdursulfaseSETQANSTTDALNVLLIIVD Full view525IaMetabolicElapraseSHIRESterile, nonpyrogenic clear to slightly opalescent, colorless solution that must be diluted prior to administration in 0.9% Sodium Chloride Injection, USPIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Heparan sulfate,Perilipin-3
1482Th1100PramlintideKCNTATCATQRLANFLVHSS Full view37IaHormonal/MetabolicSymlinAmylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca)Clear, isotonic, sterile solutionSubcutaneous injectionN.A. Calcitonin receptor,Receptor activity-modifying protein 1,Receptor activity-modifying protein 2,Receptor activity-modifying protein 3
1494Th1101GalsulfaseSGAGASRPPHLVFLLADDLG Full view497IaMetabolicNaglazymeBioMarinSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted with 0.9% Sodium Chloride Injection, USP, prior to administrationIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Perilipin-3
1502Th1105Insulin AspartA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicNovoLogNovo NordiskSterile, aqueous, clear, and colorless solutionSubcutaneous injection, Intravenous injectionHypoglycemic Agents and Antidiabetic Agents Insulin receptor
1503Th1105Insulin AspartA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicNovoLog Mix 50/50Novo NordiskUniform, white, sterile suspension that contains insulin aspartSubcutaneous injectionHypoglycemic Agents and Antidiabetic Agents Insulin receptor
1504Th1105Insulin AspartA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicNovoLog Mix 70/30Novo NordiskUniform, white, sterile suspension that contains insulin aspart 100 Units/mL.Subcutaneous injectionHypoglycemic Agents and Antidiabetic Agents Insulin receptor
1511Th1106Insulin DetemirA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicLEVEMIRNovo NordiskClear, colorless, aqueous, neutral sterile solutionSubcutaneous injectionAntidiabetic Agents Insulin receptor
1602Th1128Velaglucerase AlfaARPCIPKSFGYSSVVCVCNA Full view497IaHormonalVPRIVShireSterile, preservative free, lyophilized powderIntravenous infusionEnzymes Glucosylceramidase