A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1001 | Th1001 | Lepirudin | LVYTDCTESGQNLCLCEGSN Full view | 65 | Ia | Hematological,Metabolic | Refludan | Berlex Labs | Sterile, white, freeze-dried powder | Intravenous infusion | Antithrombins and Fibrinolytic Agents | Prothrombin |
1032 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiomax | Medicines Co or MDCO | White lyophilized cake in single-use vials | Intravenous infusion | Antithrombins | Prothrombin |
1033 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiox | The Medicines Company UK Ltd | Powder for concentrate for solution | Injection | Antithrombins | Prothrombin |
1055 | Th1009 | Alteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | Activase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous | Thrombolytic Agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1064 | Th1011 | Darbepoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Aranesp | Amgen Inc | Sterile, colorless, preservative-free solution containing polysorbate | Intravenousor Subcutaneous administration | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1067 | Th1012 | Reteplase | SYQGNSDCYFGNGSAYRGTH Full view | 255 | Ib | Hematological,Metabolic | Retavase | Centocor | Sterile, white, lyophilized powder | Intravenous Injection | Fibrinolytic Agents, Thrombolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1071 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Binocrit | Sandoz | Clear colourless solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1072 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epocept | Lupin pharma | N.A. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1073 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epofit | Intas pharma | N.A. | N.A. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1074 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogen | Amgen Inc. | Sterile, colorless liquid | Subcutaneous Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1075 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogin | Chugai | N.A. | Subcutaneous or by Intravenous. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1076 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Eprex | Janssen-Cilag. Ortho Biologics LLC | Solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1077 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Nanokine | Nanogen Pharmaceutical biotechnology, Vietnam) | Sterile, white, lyophilized powder. The reconstituted preparation with 1 ml solvent (containing 0.9% benzyl alcohol) results in a clear, colorless solution. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1078 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Procrit | Ortho Biotech | Sterile, colorless liquid in an isotonic sodium chloride/sodium citrate buffered solution or a sodium chloride/sodium phosphate buffered solution | Intravenous(IV) or Subcutaneous (SC) administration. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1148 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Advate | N.A. | Powder form | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1149 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Alphanate | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1150 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Bioclate | Baxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc. | Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powder | Intravenous infusion | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1151 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Helixate FS | N.A. | Sterile, stable, purified, nonpyrogenic, dried concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1152 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hemofil M | N.A. | Dry concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1153 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hyate:C | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1154 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Koate-HP | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1155 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Kogenate FS | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1156 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monarc-M | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1157 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monoclate-P | N.A. | Lyophilized powder for solution | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1158 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | ReFacto | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1159 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Xyntha | N.A. | Sterile, nonpyrogenic, preservative-free, freeze-dried powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1201 | Th1026 | Anistreplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ic | Hematological,Metabolic | Eminase | Wulfing Pharma GmbH | Dry powder | Intravenous infusion | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1210 | Th1028 | Tenecteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | TNKase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous Injection | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein |
1234 | Th1032 | Coagulation factor VIIa | ANAFLEELRPGSLERECKEE Full view | 255 | Ib | Hematological,Metabolic | NovoSeven | Novo Nordisk | Sterile, white lyophilized powder | Injection | Thrombotic Agents, Coagulants | Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor |
1288 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Cordase | N.A. | N.A. | N.A. | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1289 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Santyl | Advance Biofactures Corp | Sterile enzymatic debriding ointment | External use only | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1290 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Xiaflex | Auxilium | Sterile lyophilized powder (white cake) | Intralesional Injection | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1361 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albuminar | CSL Behring | Sterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process. | Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1362 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albutein | GRIFOLS | Sterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume). | Albutein 20% is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1363 | Th1052 | Eptifibatide | Mpr-Har-Gly-Asp-Trp- Full view | 7 | Ib | Hematological/Metabolic | INTEGRILIN | Schering-Plough/Essex | Clear, colorless, sterile, non-pyrogenic solution of Eptifibatide | Injection Solution for IIntravenousUse | Platelet Aggregation Inhibitors | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
1365 | Th1053 | Serum albumin iodonated | MKWVTFISLLFLFSSAYSRG Full view | 600 | IV | Hematological Disorders | Megatope | IsoTex Diagnostics | Colorless to very pale yellow solutions | Injection for Intravenous administration | Diagnostic Agents | Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP |
1366 | Th1053 | Serum albumin iodonated | MKWVTFISLLFLFSSAYSRG Full view | 600 | IV | Hematological Disorders | Jeanotope | IsoTex Diagnostics | Sterile, nonpyrogenic, aqueos solution | Intravenous infusion | Diagnostic Agents | Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP |
1367 | Th1053 | Serum albumin iodonated | MKWVTFISLLFLFSSAYSRG Full view | 600 | IV | Hematological Disorders | Volumex | IsoTex Diagnostics | Colorless to very pale yellow. | Intravenous infusion | Diagnostic Agents | Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP |
1453 | Th1083 | Coagulation Factor Ix | YNSGKLEEFVQGNLERECME Full view | 415 | Ia | Hematological/Metabolic/genetic | Alprolix | Biogen Idec Inc., and Genentech USA, Inc | Sterile, non-pyrogenic, preservative-free, white to off-white, lyophilized powder to cake for reconstitution with the provided diluent | Intravenous infusion | Coagulants and Thrombotic Agents | N.A. |
1475 | Th1095 | Ranibizumab | Light Chain SASQDISN Full view | 447 | IIa | Hematological/Eye Disorder | Lucentis | Genentech | Sterile, colorless to pale yellow solution | Intravitreal injection | Ophthalmics | Vascular endothelial growth factor A |
1529 | Th1108 | Pegaptanib | N.A. Full view | 0 | IIa | Hematological/Eye Disorder | Macugen | Gilead Sciences | Sterile, aqueous solution containing pegaptanib sodium for intravitreous injection | Intravitreal injection | Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. | N.A. |
1549 | Th1118 | Sulodexide | N.A. Full view | 0 | IIIc | Hormonal/genetic/Hematological/N.A. | SULODEXIDE | Syntex S.A | N.A. | N.A. | Antithrombins and Fibrinolytic Agents and Hypoglycemic Agents and Anticoagulants and Hypolipidemic Agents | Heparin cofactor 2,Antithrombin-III |
1637 | Th1143 | Fibrinolysin Aka Plasmin | Fibrinolysin heavy c Full view | 786 | Ic | Hematological | Elase | N.A. | N.A. | N.A. | N.A. | N.A. |
1684 | Th1164 | Antithrombin Alfa | NA Full view | 0 | Ia | Hematological Disorders | Atryn | Gtc Biotherapeutics, Inc. | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | NA |
1685 | Th1164 | Antithrombin Alfa | NA Full view | 0 | Ia | Hematological Disorders | Atryn | R Evo Bioloigics, Inc. | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | NA |
1687 | Th1165 | Antithrombin III human | NA Full view | 0 | Ia | Hematological Disorders | Thrombate III | GRIFOLS USA, LLC | kit | NA | NA | NA |
1688 | Th1165 | Antithrombin III human | NA Full view | 0 | Ia | Hematological Disorders | Thrombate III | Grifols Therapeutics Inc | Powder for Solution | NA | NA | NA |
1691 | Th1165 | Antithrombin III human | NA Full view | 0 | Ia | Hematological Disorders | Thrombate III Pws IV 1000iu/vial | Miles Inc. Pharmaceutical Division | Powder for Solution | NA | NA | NA |
1719 | Th1172 | Coagulation Factor XIII A-Subunit (Recombinant) | NA Full view | 0 | Ia | Hematological Disorders | Tretten | Novo Nordisk | Kit | Intravenous | NA | NA |
1720 | Th1172 | Coagulation Factor XIII A-Subunit (Recombinant) | NA Full view | 0 | Ia | Hematological Disorders | Tretten | Novo Nordisk Canada Inc | Powder for Solution | Intravenous | NA | NA |