SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1544
Primary information
SAPdb_ID1544
PMID21221462
Year2011
NameCha-Ala-Phe (Cyclohexylalanine- Phenylalanine)
SequenceCha-AF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-terminal ModicationCha=Cyclohexylalanine
Length2
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNone
TechniqueTransmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
SolventHFP (1,1,1,3,3,3-hexafluoro-2-propanol) + water
Method1mg of a purified peptide in 50 ml of HFIP and by subsequent addition of 1 ml of double distilled water. Samples were aged for 2– 24 hours.
Concentration1 mg/ml
pHNA
Temperature
Room temperature
Incubation Period2 -24 hours
Self-Assembly FormationYes
Type of Self-AssemblyVesicular and fibrillar assemblies
Size of Self-Assembled structureDiameter: ~ 50nm (vesicle); diameter: ~ 20nm (fibrillar structure)
Linear/CyclicLinear
Stability of NanostructureThermally stable < 55°C; stable under wide range of pH
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN[C@@H](CC1CCCCC1)C(=O)N[C@@H](Cc1ccccc1)C=O