Details of SAPdb ID 1308 |
Primary information | ||
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SAPdb_ID | 1308 | |
PMID | 23061818 | |
Year | 2012 | |
Name | Boc-Phe-Phe-OH and NH2-Phe-Phe-OH | |
Sequence | FF | |
N-Terminal Modification | Boc (or t-butoxycarbonyl) | |
C-Terminal Modification | Free | |
Non-terminal Modication | None | |
Length | 2 | |
Peptide/Conjugate/Mixture | Mixture | |
Conjugate Partner | Boc-Phe-Phe-OH + NH2-Phe-Phe-OH | |
Technique | Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy) | |
Solvent | HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl | |
Method | To coassemble the two peptides, we dissolved each peptide in 1,1,1,3,3,3-hexafluoro-2-propanol (HFP) and diluted them in 50% ethanol. The polarized solvent allowed the selfassembly of peptides. | |
Concentration | 5mg/ml (1st dipeptide) + 4mg/ml )2nd dipeptide | |
pH | ~ 4.5 | |
Temperature | Room temperature | |
Incubation Period | 10 -24 hours | |
Self-Assembly Formation | Yes | |
Type of Self-Assembly | Necklaces like Nanostructue | |
Size of Self-Assembled structure | Spherical assemblies with diameter 1-4Œºm; elongated structures with diameter : ‚à º300 to 800 nm | |
Linear/Cyclic | Linear | |
Stability of Nanostructure | Unstable at 70°C | |
Comment | Co-assembly of two dipeptides | |
Secondary information | ||
Physico-Chemical properties |
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STRUCTURE |
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SMILES | N.A. |