SAPdb: Entry Card with Detailed Information of Peptide

Welcome to Entry Card of Peptide


Details of SAPdb ID 1304
Primary information
SAPdb_ID1304
PMID23061818
Year2012
NameBoc-Phe-Phe-OH and NH2-Phe-Phe-OH
SequenceFF
N-Terminal ModificationBoc (or t-butoxycarbonyl)
C-Terminal ModificationFree
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixtureMixture
Conjugate PartnerBoc-Phe-Phe-OH + NH2-Phe-Phe-OH
TechniqueScanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
SolventHFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl
MethodTo coassemble the two peptides, we dissolved each peptide in 1,1,1,3,3,3-hexafluoro-2-propanol (HFP) and diluted them in 50% ethanol. The polarized solvent allowed the selfassembly of peptides.
Concentration3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide
pH~ 4.5
Temperature
Room temperature
Incubation Period10 -24 hours
Self-Assembly FormationYes
Type of Self-AssemblyNecklaces like Nanostructue
Size of Self-Assembled structureSpherical assemblies with diameter 1-4μm; elongated structures with diameter : ∼300 to 800 nm
Linear/CyclicLinear
Stability of NanostructureUnstable at 70°C
CommentCo-assembly of two dipeptides
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.