SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1217
Primary information
SAPdb_ID1217
PMID25621167
Year2015
NameDiPhenylalanine
SequenceFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNA
TechniqueFE - SEM (Field Emission Scanning Electron Microscopy or FE - SEM)
SolventWater
MethodFresh stock solutions of Phe were prepared by dissolving Phe in distilled water at concentrations of 10, 25, 50, 100, and 150 mM. Fibril structure formed by following two techniques: (1)Conventional drop-casting: 3 mL of Phe–Phe solution was dropped on a clean stainless steel substrate and allowed to dry at 25°C in a vacuum for 12 h prior to subsequent characterization; (2) Directional freeze-drying: 1.5 mL of Phe–Phe solution was pipetted into a 2 mL centrifuge tube. The tube was placed into liquid nitrogen or a 20°C or 80°C freezer
Concentration2mM
pH7
Temperature
(-)20 °C
Incubation PeriodNA
Self-Assembly FormationYes
Type of Self-AssemblyNanofiber
Size of Self-Assembled structureDiameter ~ 160nm, Length >10micrometer
Linear/CyclicLinear
Stability of NanostructureNA
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O