|
|
|
|
Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us |
|
| PolysacDB ID | 2419 |
| Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed Function | This Carbohydrate is highly immunodominant |
| Antigenic Nature | Sera of humans having IgM myeloma |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab AC8 |
| Antibody Type Class | IgM |
| Assay System | Solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay |
| Cross Reactivity | AC8 agglutinated preferentially group A streptococci |
| Proposed Epitope | AC8 appears to be specific for N-acetly-D-glucosamine (GlcNAc) side chains β(1-->2)-linked to rhamnose |
| IEDB Epitope | 76687 |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 07-05-2011 |
| References | 2579417 |
| PolysacDB ID | 2420 |
| Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed Function | This Carbohydrate is highly immunodominant |
| Antigenic Nature | Sera of humans having IgM myeloma |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab AC179 |
| Antibody Type Class | IgM |
| Assay System | Solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay |
| Cross Reactivity | ACI79 was most active in agglutinating A variant (Av) and group C streptococci |
| Proposed Epitope | AC179 is directed to α-linked rhamnose oligosaccharides |
| IEDB Epitope | 76687 |
| Proposed Utility | AC179 induced complement activation in the presence of the carbohydrate |
| Curator ID | AA + AS |
| Date of Curation | 07-05-2011 |
| References | 2579417 |
| PolysacDB ID | 2426 |
| Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed Function | This Carbohydrate is highly immunodominant |
| Antigenic Nature | Whole cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Antisera |
| Antibody Type Class | N/A |
| Assay System | Radioimmunoassay |
| Cross Reactivity | N/A |
| Proposed Epitope | The antigenic determinant was known as α hapten that had a estimated molecular weight of 1100 daltons and a rhamnose: glucosamine molar ratio of 6:1 |
| IEDB Epitope | 76687 |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 10-05-2011 |
| References | 4795261 |
|
Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |