PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1330
Carbohydrate NamePhosphomannan Complex   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameCandida albicans   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab B6.1
Antibody Type ClassIgM
Assay SystemELISA, Immunofluorescence and immunoblotting
Cross ReactivityN/A
Proposed Epitopeβ-1,2-mannotriose residues of the L-mannan constitute an important part of the epitope
IEDB Epitope76920
Proposed UtilityMAb C3.1 transfers protection against disseminated candidiasis
Curator IDAA + AS
Date of Curation14-06-2010
ReferencesPMC97325

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PolysacDB ID1331
Carbohydrate NamePhosphomannan Complex   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameCandida albicans   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab B6
Antibody Type ClassIgM
Assay SystemELISA, Immunofluorescence and immunoblotting
Cross ReactivityN/A
Proposed EpitopeN/A
IEDB Epitope76920
Proposed UtilityThis Mab can be used for epitope mapping of non-immunodominant residues of L-mannan
Curator IDAA + AS
Date of Curation16-06-2010
ReferencesPMC97325

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PolysacDB ID1332
Carbohydrate NamePhosphomannan Complex   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameCandida albicans   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab C3.1
Antibody Type ClassIgG3
Assay SystemELISA, Immunofluorescence and immunoblotting
Cross ReactivityN/A
Proposed Epitopeβ-1,2-mannotriose residues of the L-mannan constitute an important part of the epitope
IEDB Epitope76920
Proposed UtilityMAb C3.1 transfers protection against disseminated candidiasis
Curator IDAA + AS
Date of Curation16-06-2010
ReferencesPMC97325

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