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| PolysacDB ID | 1797 |
| Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugate Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
| Antibodies | Mab 10B9 |
| Antibody Type Class | IgG1 |
| Assay System | ELISA, bactericidal assays |
| Cross Reactivity | N/A |
| Proposed Epitope | The epitope was located on short internal fragments of the polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
| Curator ID | AA + AS |
| Date of Curation | 03-11-2010 |
| References | PMC2196336 |
| PolysacDB ID | 1798 |
| Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugate Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
| Antibodies | Mab 7C11 |
| Antibody Type Class | IgG1 |
| Assay System | ELISA, bactericidal assays |
| Cross Reactivity | N/A |
| Proposed Epitope | The epitope was located on short internal fragments of the polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
| Curator ID | AA + AS |
| Date of Curation | 03-11-2010 |
| References | PMC2196336 |
| PolysacDB ID | 1799 |
| Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugate Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
| Antibodies | Mab 11G1 |
| Antibody Type Class | IgG2a |
| Assay System | ELISA, bactericidal assays |
| Cross Reactivity | N/A |
| Proposed Epitope | The epitope was located on short internal fragments of the polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
| Curator ID | AA + AS |
| Date of Curation | 03-11-2010 |
| References | PMC2196336 |
| PolysacDB ID | 1800 |
| Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugate Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
| Antibodies | Mab 1F1 |
| Antibody Type Class | IgG2b |
| Assay System | ELISA, bactericidal assays |
| Cross Reactivity | N/A |
| Proposed Epitope | The epitope was located on short internal fragments of the polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
| Curator ID | AA + AS |
| Date of Curation | 04-11-2010 |
| References | PMC2196336 |
| PolysacDB ID | 1801 |
| Carbohydrate Name | N-propionylated α(2-->8)-linked sialooligosaccharides (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Neisseria meningitidis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N-propionylated α(2-->8)-linked sialooligosaccharides |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugate Method | The oligosaccharide was activated using NaIO4 at 4°C for 60 min and combined with monomeric tetanus toxoid in sodium phosphate buffer containing NaBH3CN and heated at 37°C for 5 days |
| Antibodies | Mab 11F3 |
| Antibody Type Class | IgG3 |
| Assay System | ELISA, bactericidal assays |
| Cross Reactivity | N/A |
| Proposed Epitope | The epitope was located on short internal fragments of the polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help in the elucidation of the capsular polysaccharide structure |
| Curator ID | AA + AS |
| Date of Curation | 04-11-2010 |
| References | PMC2196336 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |