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| PolysacDB ID | 2397 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus mutans BHT (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | Ethylene oxide killed cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 8A1 |
| Antibody Type Class | IgM |
| Assay System | Haemagglutination |
| Cross Reactivity | This Mab cross-reacted with LTA from L.casei 6375 but was relatively less efficient in its ability to interact with the LTAs of L. fermentum and S. faecium |
| Proposed Epitope | Glycerophosphate-glycerophosphateglycerol residue backbone seemed to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | These highly specific reagents [Mabs] should prove useful not only for affinity purification of LTAs but also for experiments designed to define the putative role(s) of LTAs in biological processes |
| Curator ID | AA + AS |
| Date of Curation | 30-04-2011 |
| References | PMC264251 |
| PolysacDB ID | 2398 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus mutans BHT (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | Ethylene oxide killed cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 8G10 |
| Antibody Type Class | IgM |
| Assay System | Haemagglutination |
| Cross Reactivity | This Mab cross-reacted with LTA from L.casei 6375 and also to some extent with the LTAs of L. fermentum and S. faecium |
| Proposed Epitope | Glycerophosphate-glycerophosphateglycerol residue backbone seemed to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | These highly specific reagents [Mabs] should prove useful not only for affinity purification of LTAs but also for experiments designed to define the putative role(s) of LTAs in biological processes |
| Curator ID | AA + AS |
| Date of Curation | 30-04-2011 |
| References | PMC264251 |
| PolysacDB ID | 2399 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus mutans BHT (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | Ethylene oxide killed cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 9F6 |
| Antibody Type Class | IgM |
| Assay System | Haemagglutination |
| Cross Reactivity | This Mab cross-reacted with LTA from L.casei 6375 but was relatively less efficient in its ability to interact with the LTAs of L. fermentum and S. faecium |
| Proposed Epitope | Glycerophosphate-glycerophosphateglycerol residue backbone seemed to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | These highly specific reagents [Mabs] should prove useful not only for affinity purification of LTAs but also for experiments designed to define the putative role(s) of LTAs in biological processes |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2400 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus mutans Ingbritt (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | Ethylene oxide killed cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 2B5 |
| Antibody Type Class | IgG1 |
| Assay System | Haemagglutination |
| Cross Reactivity | This Mab cross-reacted with LTA from L.casei 6375 but was relatively less efficient in its ability to interact with the LTAs of L. fermentum and S. faecium |
| Proposed Epitope | Glycerophosphate-glycerophosphateglycerol residue backbone seemed to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | These highly specific reagents [Mabs] should prove useful not only for affinity purification of LTAs but also for experiments designed to define the putative role(s) of LTAs in biological processes |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2401 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus mutans Ingbritt (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | Ethylene oxide killed cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 7B11 |
| Antibody Type Class | IgG3 |
| Assay System | Haemagglutination |
| Cross Reactivity | This Mab cross-reacted with LTA from L.casei 6375 and L. fermentum but was relatively less efficient in its ability to interact with the LTAs of S. faecium |
| Proposed Epitope | Glycerophosphate-glycerophosphateglycerol residue backbone seemed to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | These highly specific reagents [Mabs] should prove useful not only for affinity purification of LTAs but also for experiments designed to define the putative role(s) of LTAs in biological processes |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2402 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 6D10 |
| Antibody Type Class | IgM |
| Assay System | Haemagglutination |
| Cross Reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed Epitope | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2403 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 9E5 |
| Antibody Type Class | IgG1 |
| Assay System | Haemagglutination |
| Cross Reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed Epitope | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2404 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe Name | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed Function | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab 13G5 |
| Antibody Type Class | IgM |
| Assay System | Haemagglutination |
| Cross Reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed Epitope | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |