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| PolysacDB ID | 1178 |
| Carbohydrate Name | Lipoologosaccharide band B of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Bordetella pertusis 134 LOS B variant strain (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed Function | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab BL-8 |
| Antibody Type Class | IgM |
| Assay System | Antibody accessibility radioimmunobinding assay, Immunoblotting |
| Cross Reactivity | This Mab reacted with all B. pertussis and Bordetella bronchiseptica Vir- (avirulent) variant strains tested but is not present on Bordetella parapertussis and B. bronchiseptica Vir+ (virulent) wild-type strains |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | Moderate lytic activity against a mutant strain expressing only the LOS B band was observed with this Mab |
| Curator ID | AA + AS |
| Date of Curation | 27-02-2010 |
| References | PMC257226 |
| PolysacDB ID | 1179 |
| Carbohydrate Name | Lipoologosaccharide band B of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Bordetella pertusis 134 LOS B variant strain (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed Function | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab BL-9 |
| Antibody Type Class | IgM |
| Assay System | Antibody accessibility radioimmunobinding assay, Immunoblotting |
| Cross Reactivity | This Mab reacted with all B. pertussis and Bordetella bronchiseptica Vir- (avirulent) variant strains tested but is not present on Bordetella parapertussis and B. bronchiseptica Vir+ (virulent) wild-type strains |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 27-02-2010 |
| References | PMC257226 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |