PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Page - 1 of 1

Record - 1 of 3   [TOP]

PolysacDB ID2348
Carbohydrate NameK antigens [Capsular polysaccharide]   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameSinorhizobium meliloti strain NRG34   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe K antigens of Sinorhizobium spp. are major strain-specific antigens, which commonly consist of small repeating units of a hexose and 1-carboxy-2-keto-3-deoxy sugars, such as sialic acid or 3-deoxy-D-manno-2-octulosonic acid (Kdo), although they vary in glycosyl residue composition, substitution patterns, linkage points, anomeric configuration, and size range. The K-antigens of rhizobia do not possess a lipid anchor
BCSDB StructureN/A
Proposed FunctionK antigens may be involved in an early recognition step in S. meliloti-alfalfa interactions and that K antigen production is affected by plant-derived signals
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 7
Antibody Type ClassIgGM
Assay SystemELISA and immunoblotting
Cross ReactivityThis Mab was specific to S. melliloti
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe use of MAbs to study specific cell surface components from the bacteroids of Rhizobium leguminosarum have yielded interesting information about morphogenesis in the pea symbiont, including the temporal expression of specific epitopes during nodule development
Curator IDAA + AS
Date of Curation10-04-2011
References10543844

Record - 2 of 3   [TOP]

PolysacDB ID2349
Carbohydrate NameK antigens [Capsular polysaccharide]   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameSinorhizobium meliloti strain NRG185   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe K antigens of Sinorhizobium spp. are major strain-specific antigens, which commonly consist of small repeating units of a hexose and 1-carboxy-2-keto-3-deoxy sugars, such as sialic acid or 3-deoxy-D-manno-2-octulosonic acid (Kdo), although they vary in glycosyl residue composition, substitution patterns, linkage points, anomeric configuration, and size range. The K-antigens of rhizobia do not possess a lipid anchor
BCSDB StructureN/A
Proposed FunctionK antigens may be involved in an early recognition step in S. meliloti-alfalfa interactions and that K antigen production is affected by plant-derived signals
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 8
Antibody Type ClassIgGM
Assay SystemELISA and immunoblotting
Cross ReactivityThis Mab was specific to S. melliloti. But MAb 8 recognized the K antigens from both the homologous strain, S. meliloti NRG185, and S. meliloti NRG286
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe use of MAbs to study specific cell surface components from the bacteroids of Rhizobium leguminosarum have yielded interesting information about morphogenesis in the pea symbiont, including the temporal expression of specific epitopes during nodule development
Curator IDAA + AS
Date of Curation11-04-2011
References10543844

Record - 3 of 3   [TOP]

PolysacDB ID2350
Carbohydrate NameK antigens [Capsular polysaccharide]   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameSinorhizobium meliloti strain NRG247   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe K antigens of Sinorhizobium spp. are major strain-specific antigens, which commonly consist of small repeating units of a hexose and 1-carboxy-2-keto-3-deoxy sugars, such as sialic acid or 3-deoxy-D-manno-2-octulosonic acid (Kdo), although they vary in glycosyl residue composition, substitution patterns, linkage points, anomeric configuration, and size range. The K-antigens of rhizobia do not possess a lipid anchor
BCSDB StructureN/A
Proposed FunctionK antigens may be involved in an early recognition step in S. meliloti-alfalfa interactions and that K antigen production is affected by plant-derived signals
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 9
Antibody Type ClassIgM
Assay SystemELISA and immunoblotting
Cross ReactivityThis Mab was specific to S. melliloti
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe use of MAbs to study specific cell surface components from the bacteroids of Rhizobium leguminosarum have yielded interesting information about morphogenesis in the pea symbiont, including the temporal expression of specific epitopes during nodule development
Curator IDAA + AS
Date of Curation11-04-2011
References10543844

Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020