PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

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PolysacDB ID	1067
Carbohydrate Name	Enterobacterial common antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Escherichia coli C600 (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a glycophospholipid built up by an amino sugar heteropolymer linked to an L-glycerophosphatidyl residue.
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole formalinized E. coli C600 cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 865
Antibody Type Class	IgM
Assay System	ELISA and immunoblotting
Cross Reactivity	This antibody cross-reacted with purified ECA from S.montevideo and to E. coli Rl and R4 LPS, cross-reacted well with the K5 capsular polysaccharide
Proposed Epitope	Epitope was proposed to contain 4-linked α-N-acetylglucosamine
IEDB Epitope	N/A
Proposed Utility	This Mab may be used for the detection of ECA and K5 core structures but also for analysis of the molecular forms resolved on polyacrylamide gels (banding patterns)
Curator ID	AA + AS
Date of Curation	20-01-2010
References	PMC261975

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PolysacDB ID	1068
Carbohydrate Name	Enterobacterial common antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Escherichia coli C600 (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a glycophospholipid built up by an amino sugar heteropolymer linked to an L-glycerophosphatidyl residue.
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole formalinized E. coli C600 cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 898
Antibody Type Class	IgG2a
Assay System	ELISA and immunoblotting
Cross Reactivity	This antibody did not cross-react with K5 capsular polysaccharide
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab may be used for the detection of ECA core structures but also for analysis of the molecular forms resolved on polyacrylamide gels (banding patterns)
Curator ID	AA + AS
Date of Curation	20-01-2010
References	PMC261975

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PolysacDB ID	1090
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Entamoeba histolytica (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Plasma membrane and whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 2D7.10
Antibody Type Class	IgG2b
Assay System	ELISA, immunoblotting
Cross Reactivity	This antibody Was specific to Entamoeba histolytica and did not cross-react with the other Entamoeba isolates
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab would help in the study of carbohydrate antigens that may have relevance in the studies on the mechanism of pathogenicity of the microbe.
Curator ID	AA + AS
Date of Curation	27-01-2010
References	PMC313678

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PolysacDB ID	1105
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Actinobacillus pleuropneumoniae serotype 4 (field isolate F6) (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Formalin-fixed A. pleuropneumoniae serotype 4 cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 6F7
Antibody Type Class	IgM
Assay System	Whole cell ELISA and slide agglutination tests
Cross Reactivity	This Mab failed to recognize surface epitopes located on other bacterial, such as H. parasuis, P. haemolytica, P. multocida capsular types A and D, Haemophilus taxon minor group, and A. suis, K. pneumoniae and B. bronchiseptica. were reactive with 26 serotype 4 isolates,11 serotype 7 isolates, and 1 each of the serotype 1 and non-typeable isolates tested
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This MAb could be useful for the serological diagnostic of animals infected with serotypes 4 and 7 by inhibition ELISA or competition ELISA. Moreover, they could be useful as complementary reagents to polyclonal sera for serotyping of field isolates belonging to A. pleuropneumoniae serotype 4 or 7
Curator ID	AA + AS
Date of Curation	31-01-2010
References	PMC170200

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PolysacDB ID	1127
Carbohydrate Name	CA antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Aspergillus fumigatus 2085 (NCBI Taxonomy) (Drugpedia)
Basic Structure	Galactomannans are composed of an α-1,6-linked mannan backbone substituted with mannopyranose oligosaccharides and immunodominant terminal galactofuranose present either singly or linked to oligogalactosides
BCSDB Structure	N/A
Proposed Function	The wide distribution and similar chemical structure of the galactomannans have been responsible for serologic cross-reactions
Antigenic Nature	Cell walls of A. fumigatus 2085
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab SC1
Antibody Type Class	IgM
Assay System	Enzyme Immunoassay, Precipitin reactions, Immunoblotting, Immunofluorescence assays
Cross Reactivity	MAb SC1 was reactive with other Aspergillus species, Fusarium sp., and dermatophytes
Proposed Epitope	Galactomannan residues seemed to be the part of immunodominant region
IEDB Epitope	N/A
Proposed Utility	These MAbs will be useful as immunoprobes for studying epitopes responsible for the shared antigenicity of fungal mannans and galactomannans and for examining their expression during hyphal and conidial morphogenesis
Curator ID	AA + AS
Date of Curation	07-02-2010
References	PMC258783

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PolysacDB ID	1128
Carbohydrate Name	CA antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Aspergillus fumigatus 2085 (NCBI Taxonomy) (Drugpedia)
Basic Structure	Galactomannans are composed of an α-1,6-linked mannan backbone substituted with mannopyranose oligosaccharides and immunodominant terminal galactofuranose present either singly or linked to oligogalactosides
BCSDB Structure	N/A
Proposed Function	The wide distribution and similar chemical structure of the galactomannans have been responsible for serologic cross-reactions
Antigenic Nature	Cell walls of A. fumigatus 2086
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab SC40
Antibody Type Class	IgG
Assay System	Enzyme Immunoassay, Precipitin reactions, Immunoblotting, Immunofluorescence assays
Cross Reactivity	MAb SC40 was reactive with other Aspergillus species, Fusarium sp., and dermatophytes.also cross-reacted to mannans of Candida albicans serotype A and B, C.tropicalis
Proposed Epitope	Galactomannan residues seemed to be the part of immunodominant region
IEDB Epitope	N/A
Proposed Utility	These MAbs will be useful as immunoprobes for studying epitopes responsible for the shared antigenicity of fungal mannans and galactomannans and for examining their expression during hyphal and conidial morphogenesis
Curator ID	AA + AS
Date of Curation	08-02-2010
References	PMC258783

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PolysacDB ID	1139
Carbohydrate Name	58 Kda antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Aspergillus fumigatus (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	A. fumigatus mycelial extract
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 2-2-1
Antibody Type Class	IgG1
Assay System	Immunoblotting, immunoprecipitation, immunodiffusion
Cross Reactivity	This antibody cross-reacted with a 55 kDa antigen Candida albicans extract
Proposed Epitope	The epitope was proposed to consist of mannan residues
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	14-02-2010
References	PMC257743

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PolysacDB ID	1140
Carbohydrate Name	58 Kda antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Aspergillus fumigatus (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	A. fumigatus mycelial extract
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 2-2-4
Antibody Type Class	IgG1
Assay System	Immunoblotting, immunoprecipitation, immunodiffusion
Cross Reactivity	This antibody cross-reacted with a 55 kDa antigen Candida albicans extract
Proposed Epitope	The epitope was proposed to consist of mannan residues
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	14-02-2010
References	PMC257743

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PolysacDB ID	1141
Carbohydrate Name	58 Kda antigen (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Aspergillus fumigatus (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	A. fumigatus mycelial extract
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 2-2-6
Antibody Type Class	IgG1
Assay System	Immunoblotting, immunoprecipitation, immunodiffusion
Cross Reactivity	This antibody cross-reacted with a 55 kDa antigen Candida albicans extract
Proposed Epitope	The epitope was proposed to consist of mannan residues
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	14-02-2010
References	PMC257743

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PolysacDB ID	1152
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Bacteroides fragilis NCTC 9343 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab QUBF 12
Antibody Type Class	IgG1
Assay System	Immunoblotting, immunofluorescence, flow cytometry
Cross Reactivity	This Mab cross-reacted with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. All reacted with B. fragilis strain BE4
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab may help in the elucidation of variability of surface polysaccharide structures
Curator ID	AA + AS
Date of Curation	18-02-2010
References	PMC96751

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PolysacDB ID	1263
Carbohydrate Name	Glucomannoprotein (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans serotype A (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Glucomannoprotein-rich antigenic extract (GMP)
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab AF-1
Antibody Type Class	IgM
Assay System	ELISA, immunofluorescence and slide agglutination tests
Cross Reactivity	This Mab cross-reacted with C. albicans serotypes A and B, C. tropicalis, C. guilliermondii and C. viswanathii, but did not cross-react with C. krusei, C. parapsilosis, C. kefyr (pseudotropicalis) and T. Glabrata
Proposed Epitope	The epitope was proposed to consist of mannan residues
IEDB Epitope	N/A
Proposed Utility	This Mab had strong agglutination properties for Candida species. This Mab helped in the identification of new polysaccharide epitopes on the cell wall of pathogenic Candida species.
Curator ID	AA + AS
Date of Curation	02-05-2010
References	2462051

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PolysacDB ID	1264
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans Serotype A strain VW.32 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	UV-killed C. albicans strain VW.32 germ tubes
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 3b7
Antibody Type Class	IgM
Assay System	ELISA, Immunofluorescence
Cross Reactivity	This antibody cross-reacted with Candida albicans strain 3153A, strain 996B; Candida tropicalis strain Ct V. did not cross-react with other Candida species such as Candida glabrata, Candida albicans strain 995A and strain L; Candida pseudotropicalis, Candida krusei, Candida parapsilosis
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab may help in studying antigens that are involved in pathogenocity
Curator ID	AA + AS
Date of Curation	02-05-2010
References	3058980

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PolysacDB ID	1265
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab C6
Antibody Type Class	IgM
Assay System	ELISA, immunoelecton microscopy and agglutination tests
Cross Reactivity	This antibody cross-reacted with 30 strains of Candida albicans strains, 2 strains of Candida tropicalis but did not cross-react with Candida paratropicalis, Candida parapsilosis, T. glabrata and S. cerevisae.
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab had a agglutinating activity against Candida albicans
Curator ID	AA + AS
Date of Curation	02-05-2010
References	3280163

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PolysacDB ID	1266
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Fractions enriched for mitochondria and other membranous vesicles [membranous fraction] of Candida albicans
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 10G
Antibody Type Class	IgM
Assay System	ELISA, immunocollidal gold electron microscopy, indirect immunofuorescence assay, immunoelectrophoresis
Cross Reactivity	Yeast cells of 15 additional C. albicans strains and isolates of C. stellatoidka, C. tropicalis, C. intermedia and C. lusitaniae were also agglutinated by mAb 1OG. The antigen was not detected on other fungi, including Can&& krusei, C.utilis, Cryptococcus neoformans, Cr. albidus, Torulopsis glabrata, Rhodotorula spp. and Saccharomyces cerevisiae
Proposed Epitope	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab had a agglutinating activity against Candida albicans
Curator ID	AA + AS
Date of Curation	03-05-2010
References	3280163

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PolysacDB ID	1267
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 6A1
Antibody Type Class	IgM
Assay System	ELISA, Enzyme Immunoassay and Slide agglutination
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	03-05-2010
References	3280163

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PolysacDB ID	1268
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 6f8
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	03-05-2010
References	3280163

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PolysacDB ID	1269
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 6g12
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	03-05-2010
References	3280163

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PolysacDB ID	1270
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 6h9
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	03-05-2010
References	3280163

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PolysacDB ID	1271
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 7a2
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	05-05-2010
References	3280163

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PolysacDB ID	1272
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 7g12
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	05-05-2010
References	3280163

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PolysacDB ID	1273
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 8b2
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	05-05-2010
References	3280163

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PolysacDB ID	1274
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 8o4
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	06-05-2010
References	3280163

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PolysacDB ID	1275
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 8h4
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	06-05-2010
References	3280163

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PolysacDB ID	1276
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 9o4
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	07-05-2010
References	3280163

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PolysacDB ID	1277
Carbohydrate Name	Phosphomannan protein complex (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans NIH B-792 (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Heat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 9c5
Antibody Type Class	IgM
Assay System	N/A
Cross Reactivity	This antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0587
Proposed Epitope	The epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB Epitope	N/A
Proposed Utility	Antibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator ID	AA + AS
Date of Curation	07-05-2010
References	3280163

Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020