PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1382
Carbohydrate NameGP15 glycoprotein   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameCryptosporidium parvum   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureOocysts of C. Parvum
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5C3
Antibody Type ClassIgA
Assay SystemELISA, immunoblotting and immunoelectron microscopy
Cross ReactivityThis Mab did not cross-react with Cryptosporidium. Baileyi, Cryptosporidium muris, Cryptosporidium serpentis, Besnoitia darlingi,Caryospora bigenetica, Eimeria nieschulzi, E. papillata and Toxoplasma gondii
Proposed EpitopeN-acetylglucosamine residues seemed to be an important part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab showed invivo protection against Chlamydia infection
Curator IDAA + AS
Date of Curation03-07-2010
ReferencesPMC258359

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