PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1914
Carbohydrate NameComplex oligosaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NamePlasmodium yoelii   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureAedes aegypti midgut extracts
Carrier NameNil
Conjugate MethodNil
AntibodiesMab MG96
Antibody Type ClassIgG1
Assay SystemELISA, immunoblotting, immunoelectron microscopy and immunofluorescence
Cross ReactivityThis Mab shows cross-reactivity with midgut antigens from Anopheles stephensi and Anopheles gambiae
Proposed EpitopeO-linked carbohydrates seemed to be the part of the reactive epitope
IEDB EpitopeN/A
Proposed Utility Mab MG96 Completely Blocks Plasmodium yoelii Development in Anopheles stephensi
Curator IDAA + AS
Date of Curation28-11-2010
ReferencesPMC308928

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