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| PolysacDB ID | 2211 |
| Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid |
| BCSDB Structure | 3149 |
| Proposed Function | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
| Antigenic Nature | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab MATy-V7 |
| Antibody Type Class | IgM |
| Assay System | Inhibition enzyme immunoassay |
| Cross Reactivity | This Mab was specific to Vi antigen |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 04-03-2011 |
| References | 1426999 |
| PolysacDB ID | 2213 |
| Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid |
| BCSDB Structure | 3149 |
| Proposed Function | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
| Antigenic Nature | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab MATy-V1 |
| Antibody Type Class | IgM |
| Assay System | Inhibition enzyme immunoassay |
| Cross Reactivity | This Mab was specific to Vi antigen |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 06-03-2011 |
| References | 1426999 |
| PolysacDB ID | 2214 |
| Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid |
| BCSDB Structure | 3149 |
| Proposed Function | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
| Antigenic Nature | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab MATy-V5 |
| Antibody Type Class | IgM |
| Assay System | Inhibition enzyme immunoassay |
| Cross Reactivity | This Mab was specific to Vi antigen |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 08-03-2011 |
| References | 1426999 |
| PolysacDB ID | 2215 |
| Carbohydrate Name | Capsular Vi polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The salmonella Vi Capsular polysaccharide is a linear homopolymer of α[1-->4]-O-acetyl-N-acetyl-galactosaminuronic acid |
| BCSDB Structure | 3149 |
| Proposed Function | It is an important virulence factor. The Vi capsule shields the bacteria against phagocytosis by its surface negative charge properties and by covering cell-envelope components sensitive to serum opsonins |
| Antigenic Nature | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab MATy-V9 |
| Antibody Type Class | IgM |
| Assay System | Inhibition enzyme immunoassay |
| Cross Reactivity | This Mab was specific to Vi antigen |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 08-03-2011 |
| References | 1426999 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |