PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1744
Carbohydrate NameArabinogalactan and arabinomannan   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameMycobacterium tuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureMycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues, and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureM. tuberculosis culture filtrate
Carrier NameNil
Conjugate MethodNil
AntibodiesMab TB-C-1
Antibody Type ClassIgM
Assay SystemELISA, immunoblotting, Immunosorbent affinity chromatography and Immunoelectrophoresis
Cross ReactivityThis Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare
Proposed EpitopeN/A
IEDB Epitope76830
Proposed UtilityThis Mab would allow the purification of important mycobacterial antigens antigens
Curator IDAA + AS
Date of Curation20-10-2010
ReferencesPMC1577034

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