PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2462
Carbohydrate Name6B polysaccharide [octavalent polysaccharide protein conjugate vaccine, PncT]   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae serogroup 6   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureGlycoconjugate
Carrier NameNil
Conjugate MethodNil
AntibodiesHuman Antisera
Antibody Type ClassIgG
Assay SystemELISA, Opsonophagocytosis assay, in-vivo protection assay
Cross ReactivityThis antisera cross-reacts with serotype 6A
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis antisera protected mice against bacteremia and/or lung infection caused by intranasal challenge with serotypes 6B and 6A
Curator IDAA + AS
Date of Curation24-05-2011
References11110649

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