| PolysacDB ID | 1045 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella typhimurium SR-11 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is composed of three parts: (1) lipid A, (2) core polysaccharide, and (3) O antigen. The lipid A region contains two glucosamine sugar derivatives, each with three fatty acids and phosphate or pyrophosphate attached. The core polysaccharide has KDO and attached to lipid A. The side chain O is small polysaccharide chain extending outward from the core, it has several peculiar sugars and varies in composition between bacterial strains.
|
| BCSDB Structure | N/A |
| Proposed functions | LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin |
| Antigenic Nature used to produce antibodies | Live S.typhimurium SR cells. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | ST-1 |
| Antibody type and class | IgM |
| Assay System | ELISA Hemaggluttination assay |
| Cross-reactivity | This antibody was cross-reactive with Salmonella typhimurium LT-2, Salmonella typhimurium derby. |
| Proposed epitopes | O-polysaccharide |
| IEDB Epitope | N/A |
| Proposed Utility | This antibody can be used in serological assays to detect the desired antigen. |
| Curator ID | AA + AS |
| Date of Curation | 13-01-2010
|
| References | 6203984 |