PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2176
Carbohydrate NameVi antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeSalmonella typhi 620Ty   (NCBI Taxonomy)   (Drugpedia)
Basic StructureVi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesPurified Vi antigen
Carrier NameNil
Conjugation MethodNil
AntibodiesMab Vi5a
Antibody type and classIgG2b
Assay SystemPassive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
Cross-reactivityThis Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThe Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi
Curator IDAA + AS
Date of Curation22-02-2011
ReferencesPMC265979


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020