PolysacDB ID | 2024 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Pseudomonas aeruginosa (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core region of LPS is divided into the outer core and inner core. The inner core region consists of 2-keto-3-deoxyoctonic acid (KDO), heptose, phosphate, and probably ethanolamine. The outer core region commonly contains D-glucose, L-rhamnose, D-galactosamine, and L-alanine. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Formalin-killed P. aeruginosa cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab NM-3G8 |
Antibody type and class | IgM |
Assay System | ELISA, immunoblotting and flow cytometry |
Cross-reactivity | This Mab bound to P. aeruginosa strains. NM-3G8 bound to only a few strains of serotype B and M |
Proposed epitopes | This Mab reacted with the core region of the LPS |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 20-12-2010
|
References | 1564440 |