| PolysacDB ID | 2220 |
| Carbohydrate Name | Core oligosaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella typhimurium SL 1032 [Rd1] (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : L-gro-α-D-manHepp-(1-->7)-L-gro-α-D-manHepp-(1-->3)-L-gro-α-D-manHepp-(1-->5)-α-Kdop [branched to α-Kdop-(2-->4)] -(2--/lipid A/
|
| BCSDB Structure | 1784 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Heat killed bacteria |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MAST27 |
| Antibody type and class | IgG2b |
| Assay System | Enzyme immunoassay, immunoblotting |
| Cross-reactivity | This Mab was specific to Rd1 chemotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab would help elucidate the LPS core domain structure |
| Curator ID | AA + AS |
| Date of Curation | 10-03-2011
|
| References | 1383323 |