| PolysacDB ID | 2032 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Pseudomonas aeruginosa (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core region of LPS is divided into the outer core and inner core. The inner core region consists of 2-keto-3-deoxyoctonic acid (KDO), heptose, phosphate, and probably ethanolamine. The outer core region commonly contains D-glucose, L-rhamnose, D-galactosamine, and L-alanine. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
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| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Heat killed Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab LBI-IC3 |
| Antibody type and class | IgG2a |
| Assay System | ELISA, immunoblotting, opsonophagocytic assay and in vivo protection assay |
| Cross-reactivity | This Mab reacted strongly with 06a,6b, weakly with 06a,6c, Fisher IT-l and Habs 06, and not at all with 06a, 6d |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab demonstrated opsonophagocytic killing of 06 subtype strains in the presence of human peripheral blood leukocytes and fresh human serum. This Mab also showed in vivo protection |
| Curator ID | AA + AS |
| Date of Curation | 23-12-2010
|
| References | PMC186240 |