PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1542
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeLeishmania tropica (LRC-L137)   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesL. tropica (LRC-L137) promastigotes
Carrier NameNil
Conjugation MethodNil
AntibodiesMab L-5-85
Antibody type and classIgG2a
Assay SystemSolid-phase radioimmunoassay, Indirect fluorescent antibody test
Cross-reactivityThis Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It also cross-reacted with L. enriettii L144 strain
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would allow the study of the origin and the location of the Leishmania spp. antigens on the macrophage membrane as well as the characterization of these antigens in terms of their relationship to host histocompatibility antigens involved in antigen presentation
Curator IDAA + AS
Date of Curation03-09-2010
ReferencesPMC347485


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