PolysacDB ID | 1743 |
Carbohydrate Name | Phenolic glycolipid TB antigen (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Mycobacterium tuberculosis canetti (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Phenolic glycolipid consist of phenol phthiocerol as a common structure and a carbohydrate determinant that consists of 2,3,4-Me3Fuc-Rha-2-O-MeRha residues
|
BCSDB Structure | N/A |
Proposed functions | It has been widely used for the serodiagnosis of leprosy and has been implicated in the pathogenesis of leprosy |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab III604 |
Antibody type and class | IgG3 |
Assay System | ELISA and dot ELISA |
Cross-reactivity | This Mab was specific to M. tuberculosis phenolic glycolipid and did not cross-react with other phenolic glycolipids from Mycobacterium leprae, M. bovis, and M. kansasii |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab may be useful as a diagnostic reagent |
Curator ID | AA + AS |
Date of Curation | 20-10-2010
|
References | PMC270589 |