| PolysacDB ID | 2505 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Vibrio cholerae serogroup O139 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | N/A |
| Proposed functions | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
| Antigenic Nature used to produce antibodies | Acetone-treated whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab ICL11 |
| Antibody type and class | IgG3 |
| Assay System | Enzyme-linked immunosorbent assay, slide agglutination test, motility inhibition test, and indirect immunofluorescence test |
| Cross-reactivity | This Mab was specific to V. cholerae O139. No cross-reactions were seen with LPS from V cholerae 01 Inaba and Ogawa serotypes |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | All 86 cases diagnosed as V. cholerae 0139 by a rabbit polyclonal antiserum were also detected by this MAb, establishing its utility as highly sensitive and specific diagnostic reagent |
| Curator ID | AA + AS |
| Date of Curation | 08-06-2011
|
| References | 7496922 |