PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1352
Carbohydrate NameMannan   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeCandida albicans serotype A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureAn α-linked branched homopolymer of mannose linked to protein
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesHeat-killed cell suspension of C. albicans M1012(serotype A)
Carrier NameNil
Conjugation MethodNil
AntibodiesMab CA5-4
Antibody type and classIgM
Assay SystemSlide agglutination tests, immunofluorescence
Cross-reactivityThis Mab cross-reacted with C. albicans serotype B, and C. tropicalis strains
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had agglutinating properties and may be useful also as reagents for revealing the immunochemical structures of specific determinants of C. albicans cell wall mannans
Curator IDAA + AS
Date of Curation26-06-2010
ReferencesPMC268742


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