| PolysacDB ID | 1233 |
| Carbohydrate Name | Core oligosaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Brucella abortus S19 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Core oligosaccharide is composed of mannose, glucose, 2-amino-2,6-dideoxyglucose (quinovosamine), 2-amino-2-deoxyglucose (GlcN),3-deoxy-D-manno-2-octulosonic acid (KDO), and unidentified sugars. The core is linked to the lipid A, which in contrast to most LPS studied, contains both GlcN and 2,3- diamino-2,3-dideoxyglucose (GlcN3N) as backbone sugars and amide- and ester-linked long-chain saturated (C16:0 to C18:0) and hydroxylated (3-OH-C12:0, to 29-OH-C30:0) fatty acids |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Acetone-killed B. abortus S19 cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Baro-2 |
| Antibody type and class | IgM |
| Assay System | Enzyme Immunoassay,immunoblotting |
| Cross-reactivity | The Baro-2 MAb showed reactivity against LPS from E. coli Re, S. minnesota Re, S. typhimurium Rd2, and S. typhimurium Rdl |
| Proposed epitopes | 3-deoxy-D-manno-2-octulosonic acid (KDO)seems to be an important part of the epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab may help in the elucidation of epitopic distribution of Brucella abortus LPS |
| Curator ID | AA + AS |
| Date of Curation | 27-03-2010
|
| References | PMC368229 |