PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1170
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBordetella bronchiseptica   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-chain of these bacteria was reported as a homopolymer of 1,4-linked 2,3-diacetamido-2,3- dideoxy-α-galacturonic acid. This polymer contains several amidated uronic acids, the number of which varies between strains
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesLPS from B. bronchiseptica
Carrier NameNil
Conjugation MethodNil
AntibodiesMab BRg1
Antibody type and classIgM
Assay SystemELISA and ELISA Inhibition assay
Cross-reactivityThis Mab did not react with the B. pertussis LPS
Proposed epitopesBRgl interacts with a structure located at the hinge between the polymeric O-chains and a core region
IEDB EpitopeN/A
Proposed UtilityThis Mab was used for structurural elucidation of the epitope
Curator IDAA + AS
Date of Curation25-02-2010
References7524956


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020