PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 3

Entry No. - 1   [TOP]
PolysacDB ID1331
Carbohydrate NamePhosphomannan Complex   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeCandida albicans   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab B6
Antibody type and classIgM
Assay SystemELISA, Immunofluorescence and immunoblotting
Cross-reactivityN/A
Proposed epitopesN/A
IEDB Epitope76920
Proposed UtilityThis Mab can be used for epitope mapping of non-immunodominant residues of L-mannan
Curator IDAA + AS
Date of Curation16-06-2010
ReferencesPMC97325


Entry No. - 2   [TOP]
PolysacDB ID1335
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCandida albicans 3153A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesCell wall extract of wild-type Candida albicans 3153A
Carrier NameNil
Conjugation MethodNil
AntibodiesMab B6
Antibody type and classN/A
Assay SystemELISA, Immunofluorescence and immunoblotting
Cross-reactivityThis antibody cross-reacted with strain 62, B, 4C, 24, 37, 53, and 22 but did not react with 4A, 16, 28 and 47 strains
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation18-06-2010
ReferencesPMC281022


Entry No. - 3   [TOP]
PolysacDB ID1697
Carbohydrate Name4.5-6 KDa antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeMycobacterium leprae   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesSoluble sonicate
Carrier NameNil
Conjugation MethodNil
AntibodiesMab B6
Antibody type and classIgG3
Assay SystemELISA, immunodiffusion, immunoblotting and inhibition assays
Cross-reactivityThis Mab was highly cross-reactive and reacted with all 14 mycobacterial strains except for M. vaccae and M. chelonei
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for antigen identification and isolation
Curator IDAA + AS
Date of Curation09-10-2010
References2415603


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