| PolysacDB ID | 2486 |
| Carbohydrate Name | Glycoprotein GP72 (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Trypanosoma cruzi Z2 Esmeraldo/3 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | GP72 is a 72-kilodalton cell surface glycoprotein found on epimastigotes and metacyclic trypomastigotes
|
| BCSDB Structure | N/A |
| Proposed functions | GP72 may regulate T. cruzi morphogenesis in the insect vector |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 8G2 B9 |
| Antibody type and class | IgG2a |
| Assay System | ELISA, immunoblotiing, indirect immunofluorescence |
| Cross-reactivity | This Mab cross-reacted with T. cruzi BOL Z2, and Z3 but did not react with Z1 |
| Proposed epitopes | This Mab binds to phosphorylated sugar side chains, which comprise 85% of GP72 carbohydrate and contain ribose, xylose, and fucose |
| IEDB Epitope | N/A |
| Proposed Utility | Anti-T. cruzi monoclonal antibodies are considered to have important applications to epidemiological studies and the improved diagnosis and prognosis of Chagas' disease |
| Curator ID | AA + AS |
| Date of Curation | 01-06-2011
|
| References | 6380014 |