PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1111
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeActinobacillus pleuropneumoniae serotype 5 strain 91-178-2005   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure108568
Proposed functionsLPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
Antigenic Nature used to produce antibodiesFormalinized whole cell antigen (WCA)
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 6.1E7.E3
Antibody type and classIgM
Assay SystemELISA, immunoblotting
Cross-reactivityThis antibody specifically reacted with Serotype5 only
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis MAb could be useful for serotyping analysis in actinobacillus strains
Curator IDAA + AS
Date of Curation01-02-2010
References9249182


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