| PolysacDB ID | 1007 |
| Carbohydrate Name | Lipoarabinomannan (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Mycobacterium tuberculosis (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues, and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
|
| BCSDB Structure | 127448 |
| Proposed functions | T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages |
| Antigenic Nature used to produce antibodies | Heat killed Mycobacterium tuberculosis |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5c11 |
| Antibody type and class | IgM |
| Assay System | Indirect immunofluorescence, ELISA, western blotting |
| Cross-reactivity | This antibody cross-reacted with large number of mycobacterial species. |
| Proposed epitopes | Arabinose moiety of Lipoarabinomannan |
| IEDB Epitope | N/A |
| Proposed Utility | This antibody has been used in the detection of mycobacteria in clinical samples |
| Curator ID | AA + AS |
| Date of Curation | 02-01-2010
|
| References | PMC229406 |