| PolysacDB ID | 1497 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Cryptococcus neoformans Serotype A [strain 24064] (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The major component of C. neoformans capsular polysaccharide is glucurunoxylomannan [GXM] consisting of an unbranched mannose backbone substituted with xylose, glucuronic acid and O-acetyl residues
|
| BCSDB Structure | N/A |
| Proposed functions | The major component of C. neoformans capsular polysaccharide is glucurunoxylomannan [GXM] consisting of an unbranched mannose backbone substituted with xylose, glucuronic acid and O-acetyl residues |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5E9 |
| Antibody type and class | IgM |
| Assay System | ELISA |
| Cross-reactivity | This antibody reacted with 2 serotype A strains 24064 and 371 |
| Proposed epitopes | Mab 5E9 bound to de-O-acetylated GXM of strain 371 but not of strain 24064. This shows the probable epitope to be variable among strains and to be acetylation independent |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 04-08-2010
|
| References | 1583327 |