PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1253
Carbohydrate NameExopolysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeBurkholderia pseudomallei NCTC 4845   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsPolysaccharide capsule of B. pseudomallei plays a role in environmental protection, immune system evasion and attachment to epithelial cells
Antigenic Nature used to produce antibodiesHeat inactivated B. pseudomallei NCTC 4847
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 4VA5
Antibody type and classIgG1
Assay SystemELISA and immunoblotting
Cross-reactivityN/A
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis MAb demonstrated a significant protective effect against a challenge dose of B. Pseudomallei in mice
Curator IDAA + AS
Date of Curation09-04-2010
References12466403


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