| PolysacDB ID | 1377 |
| Carbohydrate Name | Gp40 glycoprotein (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Cryptosporidium parvum (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A
|
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Fixed Cryptosporidium parvum sporozoites |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 4E9 |
| Antibody type and class | IgM |
| Assay System | Immunofluorescence, immunoblotting |
| Cross-reactivity | This Mab did not react other protozoa (Giardia lamblia, E. Histolytica, Toxoplasma gondii, Trypanosoma cruzi, and L. major) and was specific for Cryptosporidium |
| Proposed epitopes | The epitope recognized by 4E9 contains α-N-acetylgalactosamine residues, which are present in a mucin-type O-glycosidic linkage |
| IEDB Epitope | N/A |
| Proposed Utility | This MAb neutralized C. parvum infection and inhibited sporozoite attachment to intestinal epithelial cells in vitro |
| Curator ID | AA + AS |
| Date of Curation | 02-07-2010
|
| References | PMC101770 |