PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1326
Carbohydrate NameGlycan fraction of a surface mannoprotein   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCandida albicans B311   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 4E6
Antibody type and classIgM
Assay SystemELISA, immunofluorescence, crossed immunoelectrophoresis
Cross-reactivityThis antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia but did not cross-react with T. glabrata and S. cerevisiae
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays
Curator IDAA + AS
Date of Curation13-06-2010
ReferencesPMC259333


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020