| PolysacDB ID | 1118 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype 1 shope 4074 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The O-polsaccharide structure is as follows :
--6)-α-D-Glcp-(1-->2)-α-L-Rhap-(l-->2)-α-L-Rhap-(1--. which is linked to 1-D-GlcpNAc chains on its rhamnopyranosyl residue via 1-->3 linkage. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formalin-fixed A. pleuropneumoniae serotype 1 cells (strain Shope 4074] |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 11C3 |
| Antibody type and class | IgM |
| Assay System | ELISA, Rapid Dot ELISA and Slide agglutination test |
| Cross-reactivity | This antibody cross-reacted with reference strains of serotypes 1, 9 and 11 |
| Proposed epitopes | N/A
|
| IEDB Epitope | N/A |
| Proposed Utility | This Mab may provide reliable specific tools for rapid serological diagnosis of animals infected with serotypes 1, 9 and 11 by inhibition or competition ELISA. Moreover, these mAbs could be useful as a complementary specific reagents to polyclonal sera for serotyping of field isolates belonging to A. pleuropneumoniae serotypes 1, 9 and 11 |
| Curator ID | AA + AS |
| Date of Curation | 04-02-2010
|
| References | 9116634 |