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| PolysacDB ID | 1204 |
| Carbohydrate Name | Smooth Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Brucella melitensis strain B115 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The S-LPS of smooth-type Brucella spp. contains two distinct antigenic determinants designated A and M |
| BCSDB Structure | N/A |
| Proposed functions | LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 05D01 |
| Antibody type and class | IgG1 |
| Assay System | ELISA and immunoblotting |
| Cross-reactivity | This antibody was specific to a common epitope on A and M polysaccharides. This Mab cross-reacted with O-PS of B. abortus 99 but did not bind to R-LPS of B. melitensis B11; also did not cross-react with Y. enterocolitica0:9 LPS |
| Proposed epitopes | This Mab was proposed to be directed to antigenic determinants present along the length of the polymeric O-chain |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 07-03-2010 |
| References | 1382111 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |