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Detailed description page of ParaPep

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1422 details
Primary information
ParaPep ID1422
PMID23615879
YEAR2004
SEQUENCEGWGSFFKKAAHVGKHVGKAALTHYL
LENGTH25
NAMEPleurocidin
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Chemical ModificationNone
DiseaseAfrican sleeping sickness
AssayAlamar Blue assay
Parasite TypeTrypanosoma brucei brucei
In-vivo/vitroIn vitro
ActivityIC100=370–740 μM
HemolysisNot reported
NatureAntimicrobial
Secondary information
STRUCTURE
3-D Structure
DSSP statesCCSSSTTSSBTTBCCSSHHHHSSCC
SMILESNCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N
External Links
PDB exactPDB partialUP exactUP exactTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1z64A NA NA NA NA NA NA