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Detailed description page of ParaPep

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1322 details
Primary information
ParaPep ID1322
PMID19057622
YEAR2009
SEQUENCEHSDAVFTDNYTRLRKQMAVKKYLNSILN
LENGTH28
NAMEVasoactive intestinal peptide
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Chemical ModificationNone
DiseaseAfrican sleeping sickness
AssayMTT assay
Parasite TypeTrypanosoma brucei brucei AnTat 1.1 (blood stage form)
In-vivo/vitroIn vitro
ActivityLD50=2.8±0.6 μM
HemolysisNot reported
NatureNeuropeptide
Secondary information
STRUCTURE
3-D Structure
DSSP statesCCCSSSCCCHHHHTTTHHHHHHHTTTCC
SMILESN[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)O
External Links
PDB exactPDB partialUP exactUP exactTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P63289 NA NA NA NA