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Detailed description page of ParaPep

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1296 details
Primary information
ParaPep ID1296
PMID21517904
YEAR2011
SEQUENCELLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
LENGTH37
NAMELL-37
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Chemical ModificationNone
DiseaseAfrican sleeping sickness
AssayAlamar Blue assay
Parasite TypeTrypanosoma brucei 427 (procyclic form)
In-vivo/vitroIn vitro
ActivityIC50=4.5 μM
HemolysisNot reported
NatureAntimicrobial
Secondary information
STRUCTURE
3-D Structure
DSSP statesCHHHHHHHHHHHHHTTTTCHHHHHHTTGGGTCSCSCC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialUP exactUP exactTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2k6oA NA NA NA J3KNB4
from
137
TO
173		 NA NA